Reciprocal Communication between FAPs and Muscle Cells via Distinct Extracellular Vesicle miRNAs in Muscle Regeneration

1 Metadata: Introduction of experimental design and protocol

2 Known-miRNA map-MCEVPs: Small RNA reads from MC-EVPs were mapped against miRBase to identify known miRNAs.

3 Known-miRNA map-FAPEVPs: Small RNA reads from FAP-EVPs were mapped against miRBase to identify known miRNAs.

4 Readcount-TMP-1: The expression of known miRNAs was normalized by TPM (Transcripts per million).

5 FAP-EVPs vs MCEVPs. differential analysis: Differential expressed miRNAs were analyzed by DEGseq and filtered with qvalue<0.01 &&|log2(foldchange)|>1.