Published February 20, 2024 | Version 1.1
Dataset Open

SCimilarity Models

Description

SCimilarity is a unifying representation of single-cell expression profiles that quantifies similarity between expression states and generalizes to represent new studies without additional training. This enables a novel cell search capability, which sifts through millions of profiles to find cells similar to a query cell state and allows researchers to quickly and systematically leverage massive public scRNA-seq atlases to learn about a cell state of interest.

This repository includes model weights, embeddings, kNN graphs, and metadata for the SCimilarity cell search model as a single tarball.

This release of the model is intended for use with v0.2.0 of the SCimilarity API.

Files

Files (30.3 GB)

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md5:546251b7c435f3b1dbe38e2e420ad57f
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Additional details

Related works

Is published in
Journal article: 10.1101/2023.07.18.549537 (DOI)

Software

Repository URL
https://github.com/Genentech/scimilarity
Programming language
Python
Development Status
Active