LIPOSPHERES DRUG DELIVERY SYSTEM OF ANTIDIABETIC DRUGS: A REVIEW

Diabetes is a long-term metabolic disease caused by insufficient insulin that is characterized by elevated blood sugar, changed metabolism of fats, proteins, and carbohydrates, and a higher risk of cardiovascular problems. Anti-diabetic medications are a great fit for liposphere drug delivery systems because to their drawbacks, which include inconsistent bioavailability, substantial first pass metabolism, and more frequent administration.  Compared to emulsions, liposomes, and microspheres, the lipospheres carrier system offers a number of benefits, including improved physical stability, reduced ingredient costs, ease of preparation and scaling up, high dispersability in an aqueous medium, high entrapment of hydrophobic drugs, controlled particle size, and extended release of entrapped drug. This review article provides a thorough understanding of diabetes, including its causes, classifications, and current treatment options. It further expands on the topic by discussing lipospheres as innovative drug delivery systems and their historical implications for the administration of anti-diabetic medications.

Keywords: Liposphere, Diabetes, Novel drug delivery system, Antidiabetic drugs