CYTOKINE PROFILE IN PATIENTS WITH GLOMERULONEPHRITIS DEPENDING ON THE CLINICAL COURSE

In recent years, convincing data have been obtained proving the link between the development of GN and "immune dysregulation", primarily concerning T-lymphocytes. Experiments have shown the damaging effect on glomeruli of a cell-mediated mechanism (Th1-type) of an adaptive immune response associated with the activity of IFN-γ. Thus, it seems that cytokines play an important role in the pathogenesis of GN.