OVERVIEW OF NANOCARRIERS AS AN ANTI-CANCER AND TREATMENT

Nanotechnology has been laboriously integrated as medicine carriers over the last many times to treat colorful cancers. The main chain in the clinical operation of cancer is the development of multidrug resistance against chemotherapeutic agents. To overcome the limitations of chemotherapy, the experimenters have been developing technological advances for significant progress in the oncotherapy by enabling the delivery of chemotherapeutic agents at increased medicine content situations to the targeted spots. Several nano- medicine delivery systems designed for excrescence- targeting are estimated in preclinical and clinical trials and showed promising issues in cancerous excrescences’ clinical operation. This review describes nanocarrier’s significance in managing different types of cancers and emphasizing nanocarriers for medicine delivery and cancer nanotherapeutics. It also highlights the recent advances in nanocarriers- grounded delivery systems, including polymeric nanocarriers, micelles, nanotubes, dendrimers, glamorous nanoparticles, solid lipid nanoparticles, and amount blotches(QDs). The nanocarrier- grounded mixes are discussed in terms of their structure, characteristics, and therapeutic applications in oncology. To conclude, the challenges and future exploration opportunities of nanocarriers in chemotherapeutics are also presented. Cancer is a complicated disease for which finding a cure presents challenges. In recent decades, new ways to treat cancer are being sought; one being nanomedicine, which manipulates nanoparticles to target a cancer and release drugs directly to the cancer cells. A number of cancer treatments based on nanomedicine are under way and mostly are in preclinical trials owing to challenges in administration, safety, and effectiveness. One alternative method for drug delivery is the use of photovoltaic nanoparticles, which has the potential to deliver drugs via light activation. The concepts are based on standard photovoltaic cell that holds opposite charges on its surfaces and releases drugs when charge intensity or polarity changes upon photo-stimulation such as from a laser source or sunlight. This review will cover some recent progress in cancer treatment using nanoparticles, including photovoltaic nanoparticles.

Keywords: nanomaterials, anticancer agents, recent advances,multidrug resistance, chemotherapy