Published November 30, 2023
| Version v1
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Complications of COVID-19 and possible role of angiotensin converting enzyme inhibitors and anti-platelet medications in lowering the risk of COVID -19 infection
Creators
- 1. Department of Pharmacology, Aditya College of Pharmacy, Surampalem, Kakinada District, Andhra Pradesh, India.
Description
COVID-19, the worldwide pandemic which effected the entire health care system, particularly showed its ill effects on patients with many comorbidities. Among the COVID-19 patients admitted in hospital, are with cardiovascular diseases and hypertension where associated with increased risk of mortality. Angiotensin converting enzyme inhibitors (ACEI) and Angiotensin receptor-II blockers (ARB) were used in the management of hypertension and these medications revealed their beneficiary actions in the conditions of COVID -19 with Hypertension. On the other hand, COVID -19 also lead to thromboembolic complications which also required Intensive Care Unit admission within patients representing a unique condition termed as Covid Associated Coagulopathy (CAC). The impact of dual anti-platelet therapy reduced the risk of mechanical ventilation, ICU admission and mortality rate among individuals effected by Covid.
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