Published January 30, 2024
| Version v1
Dataset
Open
Research data for the article "Charge of a Transmembrane Peptide Alters Its Interaction with Lipid Membranes" by Thakur et al. Colloids and Surfaces B: Biointerfaces, 2024
Description
Research data for the publication Thakur, G.C.N., Uday, A., Cebecauer, M., Roos, W.H., Cwiklik, L., Hof, M., Jurkiewicz, P., and Melcrová, A. Charge of a Transmembrane Peptide Alters Its Interaction with Lipid Membranes. Colloids and Surfaces B: Biointerfaces, 2024. https://doi.org/10.1016/j.colsurfb.2024.113765
The data set contains experimental and simulation data on the study of transmembrane peptides WALP-KD and WALP-KK4+ and their interaction with model lipid membranes. Experimental and simulation details can be found in the Materials and Methods section of the mentioned article.
The data set contains:
- Files starting with "Figure..." contain source data used for the generation of the figures in the mentioned article.
- Atomic Force Microscopy images are in the raw format as collected on JPK Nano Wizard Ultra Speed AFM.
- Force-indentation curves from the force measurements by JPK Nano Wizard Ultra Speed AFM in the *.txt format. These curves were used for the analysis of the mechanical properties of the membranes with and without the transmembrane peptides.
- Line profiles (cross-sections) over the height of the supported membranes and the surrounding support. Extracted from the height images measured on JPK Nano Wizard Ultra Speed AFM.
- Molecular Dynamic simulation data - configuration files, trajectories, density profiles of chosen parts of the membrane alongside the membrane axis. These files are in respective directories for all simulated systems: POPC 100%, POPC/POPS 80/20 mol%, and both with the addition of 3 mol% peptide WALP-KD or WALP-KK4+.
Files
AFM-images-JPK-format-Figure4_and_FigureS10.zip
Files
(28.4 GB)
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md5:094b84067e362ba222f7fe59ae6c961c
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md5:97fc9c167975bf833adc247535f6d157
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md5:ad0ac673444b5400f9443032da06dcc6
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md5:a5fe43a15d882b99760ae588d6230776
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6.9 GB | Download |