IMMUNOLOGICAL INDICATORS IN STENOSING LARINGOTRACHEITIS IN CHILDREN

The modern concept of the etiopathogenesis of laryngotracheitis takes into account the action of multiple infectious and allergic trigger factors, which are most significant in immunocompromised children. We conducted a comprehensive examination and dynamic observation of 95 children with different variants of ASLT, which were divided into 2 groups. ASLT in children revealed suppression of cellular and activation of humoral immunity. Significant changes in the immune status and cytokine level in patients with frequent relapses of ASLT were manifested by a significant increase in the levels of IL-4 and IL-1β, as well as an imbalance in interferon genesis and an increase in the level of IgE.