Magnetic Tweezers Data - Lokanathan Balaji et al. "DNA binding and bridging by human CtIP in the healthy and diseased states"
Description
These timecourses and datasets correspond to the publication: Lokanathan-Balaji et al. “DNA binding and bridging by human CtIP in the healthy and diseased states” bioRxiv 2023 (https://doi.org/10.1101/2023.12.14.571649)
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Fig4+5_Datasets.zip and Fig4+5_Timecourses.zip folders contain all the datasets and the individual timecourses, respectively, for all the conditions addressed in Figures 4 and 5:
- Bare DNA
- DNA + wild-type CtIP
- DNA + lambda CtIP
- DNA + R100W CtIP
- DNA + deltaC608 CtIP
- DNA + deltaC782 CtIP
- DNA + deltaN500 CtIP
- DNA + deltaN790 CtIP
Supp_FigS4_Datasets.zip and Supp_FigS4_Timecourses.zip folders contain all the datasets and the individual timecourses, respectively, for all the conditions addressed in Supplementary Figure S4:
- fork-end branched DNA (forked) + wild-type CtIP
- fork-end branched DNA (forked) + lambda CtIP