Published March 14, 2016
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Fig. 3 in Polyoxypregnane steroids with an open-chain sugar moiety from Marsdenia tenacissima and their chemoresistance reversal activity
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- 1. State Key Laboratory of Drug Research and Natural Products Chemistry Department, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu-Chong-Zhi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, China & Joint Research Laboratory of Promoting Globalization of Traditional Chinese Medicines between Shanghai Institute of Materia Medica,
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Fig. 3. Total cellular accumulation of cisplatin, in the presence or absence of tested compounds, in parental and Pt-resistant sublines. Parental (HEK293 pcDNA3 or HKESC-1) and cisplatin-resistant (HEK293 MRP2 stably transfected or HKESC-1 cisR) cells were incubated with cisplatin (200 µM), without or with 25 µM (+) or 50 µM (++) of the designated compounds 3–5 and tenacissoside A (T.A), for 4 h. Total cellular accumulation was assessed by atomic absorption analysis after harvesting the cells. The protein content of the samples was measured for normalization purposes. Data are presented as mean ± s.d. from three independent measurements. *p <0.05, **p <0.01, versus cisplatin alone in resistant cells.
Notes
Published as part of Yao, Sheng, To, Kenneth Kin-Wah, Ma, Liang, Yin, Chun, Tang, Chunping, Chai, Stella, Ke, Chang-Qiang, Lin, Ge & Ye, Yang, 2016, Polyoxypregnane steroids with an open-chain sugar moiety from Marsdenia tenacissima and their chemoresistance reversal activity, pp. 47-58 in Phytochemistry 126 on page 53, DOI: 10.1016/j.phytochem.2016.03.006, http://zenodo.org/record/10484880
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- Journal article: 10.1016/j.phytochem.2016.03.006 (DOI)
- Journal article: urn:lsid:plazi.org:pub:FFF2FFD6AA42FF85FFD5FFA11206BD79 (LSID)
- Journal article: https://zenodo.org/record/10484880 (URL)