Published June 30, 2019
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Fig. 4 in Indole alkaloids from Gelsemium elegans
Authors/Creators
- 1. ∗ & Lab of Toxicology and Pharmacology, Faculty of Naval Medicine, Second Military Medical University, Shanghai, 200433, China & -demethoxy-gelsemamide is an open-loop indole alkaloid and 11-demethoxy-gelsemazonamide is an aromatic azo-linked dimeric indole alkaloid. Among the five alkaloids, (4R)-19-oxo-gelsevirine N & - demethoxy-gelsemamide exhibited significant inhibitory effects on nitric oxide production in lipopolysaccharide-induced RAW 264.7 macrophage cells, with IC values of 6.18 ± 1.07 and 12.2 ± 1.02 μM, respectively.
Description
Fig. 4. Experimental and calculated ECD spectra of compound 1.
Notes
Published as part of Sun, Ming-Xue, Cui, Yan, Li, Yu, Meng, Wen-Qi, Xu, Qing-Qiang, Zhao, Jie, Lu, Jin-Cai & Xiao, Kai, 2019, Indole alkaloids from Gelsemium elegans, pp. 232-240 in Phytochemistry 162 on page 234, DOI: 10.1016/j.phytochem.2019.03.016, http://zenodo.org/record/10482294
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- Journal article: 10.1016/j.phytochem.2019.03.016 (DOI)
- Journal article: urn:lsid:plazi.org:pub:FFB05768FFFD3E28D97AFFD0FFA5FF50 (LSID)
- Journal article: https://zenodo.org/record/10482294 (URL)