Published January 4, 2024 | Version v1
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Effect of tobacco smoking and alcohol consumption on semen quality and hormone reproductive levels in infertile males: A systematic review and meta analysis

Authors/Creators

  • 1. Universitas Indonesia – Haji Adam Malik General Hospital, Medan, Indonesia
  • 2. Universitas Sumatera Utara - Haji Adam Malik General Hospital, Medan, Indonesia|Universitas Sumatera Utara Hospital – Universitas Sumatera Utara, Medan, Indonesia
  • 3. Universitas Indonesia – Cipto Mangunkusumo General Hospital, Jakarta, Indonesia

Description

Aim: This study compared semen quality, FSH, LH, and Testosterone levels in infertile males among smokers and non-smokers and semen quality among alcoholics and non alcoholics.

Methods: A literature search was conducted across five databases in December 2021. The search for this article uses specific keywords tailored to each search database's specifications.

Results: A total of 15 studies with 12,503 infertile male participants included in this study. 8,025 were non-smokers, 4,477 were smokers, 210 were alcoholics and 407 were non alcoholics. The effect of tobacco smoking on sperm were more significant in smokers than in non-smokers. Alcohol consumption affects the quality and quantity of semen. Both tobacco smoking and alcohol consumption combined may amplify their negative effects toward semen parameters.

Conclusion: Smoking and alcohol has a detrimental impact on conventional semen characteristics. Due to the harmful effects of both factors, men seeking reproduction should be advised to avoid these habits.

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Cites
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Publication: 10.1007/s00404-014-3281-x (DOI)
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