Published December 30, 2023 | Version CC BY-NC-ND 4.0
Journal article Open

Application of Hyperthermia for Cancer Treatment: Various Techniques and Recent Advancement

Creators

  • 1. Department of Pharmaceutics, Siksha 'O' Anusandhan University, Bhubaneswar, India.

Description

Abstract: Cancer is a disease characterized by uncontrollable cell division in a specific area of the body. It is a leading cause of death, and its prevalence is increasing. There are numerous techniques and protocols employed, including as chemotherapy, radiography, surgical tumor removal, etc. However, these procedures have a number of negative side effects that cause excruciating pain and intense anxiety in the patients. It has been increasingly difficult to find new cancer-fighting strategies during the past few decades. One of the best cancer treatment choices is hyperthermia, an ancient form of therapy that offers fresh hope when paired with engineering methods. This study examines the crucial data for the coupling with hyperthermia of various engineering techniques, which is carefully organized according to the techniques used, such as hyperthermic perfusion, frequency enhancers, ultrasonic hyperthermia, external radio-frequency devices, microwave hyperthermia, using a catheter, heat the target area before injecting superparamagnetic and magnetic nanoparticles.

Files

A4035124123.pdf

Files (565.4 kB)

Name Size Download all
md5:9b06935ad45c72521b5c85e648e97e5b
565.4 kB Preview Download

Additional details

Identifiers

DOI
10.54105/ijapsr.A4035.124123
EISSN
2582-7618

Dates

Accepted
2023-12-15
Manuscript received on 11 November 2023 | Revised Manuscript received on 18 November 2023 | Manuscript Accepted on 15 December 2023 | Manuscript published on 30 December 2023

References

  • Hanahan D. Hallmarks of cancer: new dimensions. Cancer discovery. 2022 Jan 1;12(1):31-46. https://doi.org/10.1158/2159-8290.CD-21-1059
  • Matthews HK, Bertoli C, de Bruin RA. Cell cycle control in cancer. Nature Reviews Molecular Cell Biology. 2022 Jan;23(1):74-88. https://doi.org/10.1038/s41580-021-00404-3
  • GLOBOCAN: Country Fast Stat. Available at:http://globocan.iarc.fr/factsheets/populations/factsheet.asp/estimated cancer incidence, mortality and prevalence worldwide in 2012
  • http://www.cancer.gov/about-cancer/treatment/types/surgery/hyperthermia-fact-sheet
  • Mallory M, Gogineni E, Jones GC, Greer L, Simone CB 2nd (August 2015). "Therapeutic hyperthermia: The old, the new, and the upcoming". Crit Rev Oncol Hematol. 97 (15): 30018–4. doi:10.1016/j.critrevonc.2015.08.003. PMID 26315383. https://doi.org/10.1016/j.critrevonc.2015.08.003
  • Javidi, Mehrdad; Heydari, Morteza; Attar, Mohammad Mahdi; Haghpanahi, Mohammad; Karimi, Alireza; Navidbakhsh, Mahdi; Amanpour, Saeid (19 December 2014). "Cylindrical agar gel with fluid flow subjected to an alternating magnetic field during hyperthermia". International Journal of Hyperthermia. 31 (1): 33–39. doi:10.3109/02656736.2014.988661. PMID 25523967. S2CID 881157. https://doi.org/10.3109/02656736.2014.988661
  • Javidi, M; Heydari, M; Karimi, A; Haghpanahi, M; Navidbakhsh, M; Razmkon, A (15 December 2014). "Evaluation of the Effects of Injection Velocity and Different Gel Concentrations on Nanoparticles in Hyperthermia Therapy". Journal of Biomedical Physics & Engineering. 4 (4): 151–162. PMC 4289522. PMID 25599061.
  • HEYDARI, MORTEZA; JAVIDI, MEHRDAD; ATTAR, MOHAMMAD MAHDI; KARIMI, ALIREZA; NAVIDBAKHSH, MAHDI; HAGHPANAHI, MOHAMMAD; AMANPOUR, SAEID (October 2015). "Magnetic Fluid Hyperthermia in a Cylindrical Gel Contains Water Flow". Journal of Mechanics in Medicine and Biology. 15 (5): 1550088. doi:10.1142/S0219519415500888 https://doi.org/10.1142/S0219519415500888
  • Kok HP, Wust P, Stauffer PR, Bardati F, Van Rhoon GC, Crezee J. Current state of the art of regional hyperthermia treatment planning: a review. Radiation Oncology. 2015 Dec;10(1):1-4. https://doi.org/10.1186/s13014-015-0503-8
  • Fiorentini G, Sarti D, Gadaleta CD, Ballerini M, Fiorentini C, Garfagno T, Ranieri G, Guadagni S. A narrative review of regional hyperthermia: updates from 2010 to 2019. Integrative cancer therapies. 2020 Oct;19:1534735420932648. https://doi.org/10.1177/1534735420932648
  • Datta NR, Kok HP, Crezee H, Gaipl US, Bodis S. Integrating loco-regional hyperthermia into the current oncology practice: SWOT and TOWS analyses. Frontiers in Oncology. 2020 Jun 12;10:819. https://doi.org/10.3389/fonc.2020.00819
  • Turner PF. Regional hyperthermia with an annular phased array. IEEE Transactions on Biomedical Engineering. 1984 Jan(1):106-14. https://doi.org/10.1109/TBME.1984.325376
  • Vertrees RA, Leeth A, Girouard M, Roach JD, Zwischenberger JB. Whole-body hyperthermia: a review of theory, design and application. Perfusion. 2002 Jul;17(4):279-90. https://doi.org/10.1191/0267659102pf588oa
  • Hall DM, Buettner GR, Oberley LW, Xu L, Matthes RD, Gisolfi CV. Mechanisms of circulatory and intestinal barrier dysfunction during whole body hyperthermia. American Journal of Physiology-Heart and Circulatory Physiology. 2001 Feb 1;280(2):H509-21. https://doi.org/10.1152/ajpheart.2001.280.2.H509
  • Sakaguchi Y, Stephens LC, Makino M, Kaneko T, Strebel FR, Danhauser LL, Jenkins GN, Bull JM. Apoptosis in tumors and normal tissues induced by whole body hyperthermia in rats. Cancer research. 1995 Nov 15;55(22):5459-64.
  • Hynynen K, Shimm D, Anhalt D, Stea B, Sykes H, Cassady JR, Roemer RB. Temperaturedistributions during clinical scanned, focused ultrasound hyperthermia treatments. Int J Hyperthermia. 1990;6: 891–908. https://doi.org/10.3109/02656739009140971
  • Lu XQ, Burdette EC, Bornstein BA, Hansen JL, Svensson GK. Design of an ultrasonic therapy system for breast cancer treatment. Int J Hyperthermia. 1996; 12:375–399 https://doi.org/10.3109/02656739609022526
  • Sekins KM, Leeper DB, Hoffman JK, Keilman GW, Ziskin MC, Wolfson MR,Shaffer TH. Feasibility of lung cancer hyperthermia using breathable perfluorochemical (PFC) liquids. Part II: Ultrasound hyperthermia. Int J Hyperthermia.2004; 20:278–99. https://doi.org/10.1080/02656730310001605528
  • José M Martínez and Boguslaw J Jarosz. 3D perfused brain phantom for interstitial ultrasound thermal therapy and imaging: design, construction and characterization, physics in medicine and biology. vol 60, number 5; Published 10 February 2015. https://doi.org/10.1088/0031-9155/60/5/1879
  • Mikaya L. D. Lumöri. Experimentally Based Modelling of Field Sources for Three-Dimensional Computation of SAR in Electromagnetic Hyperthermia and Treatment Planning, IEEE transactions on microwave theory and techniques, vol. 48, no. 9, September 2000 https://doi.org/10.1109/22.869003
  • Arora Dhiraj, Mikhail Skliar and Robert B. Roemer. Model Predictive Control of Ultrasound Hyperthermia Treatments of Cancer, Proceedings of the American Control Conference Anchorage, AK May 8-10.2002 https://doi.org/10.1109/ACC.2002.1025229
  • Fumihiro Sato, Masayuki Jojo, Hidetoshi Matsuki, Tadakuni Sato, Masahiko Sendoh, Kazushi Ishiyama, M and Ken Ichi Arai. The Operation of a Magnetic Micro machine for Hyperthermia and Its Exothermic Characteristic, IEEE Transactions on magnetic, VOL. 38, NO. 5, September 2002 https://doi.org/10.1109/TMAG.2002.802304
  • T. Juang, D. Neuman, J. Schlorff, P. R. Stauffer. Construction of a Conformal Water Bolus Vest Applicator for Hyperthermia Treatment of Superficial Skin Cancer, Proceedings of the 26th Annual International Conference of the IEEE EMBS San Francisco, CA, USA • September 1-5, 2004 https://doi.org/10.1109/TAP.2013.2293336
  • Milica Popovic and Lawrence Duong. Phased Array for Microwave Hyperthermia: A Preliminary Study in a Computational Muscle Phantom, 0-7803-8883-6/05/$20.00 ©2005 IEEE
  • Domenica A. M. Iero, Lorenzo Crocco and Tommaso Isernia. Thermal and Microwave Constrained Focusing for Patient-Specific Breast Cancer Hyperthermia: A Robustness Assessment, IEEE transaction on antennas and propagation. VOL. 62, NO. 2, February 2014
  • Jaffery p .sites, Plymouth, Philip.R, Glassel Stacy, Michael D.Millar, St.Anthony et al. Perfusion hyperthermia treatment system and method. Patent Number: 5,730,720, Date of Patent: Mar. 24, 1998
  • Ardith W. El-Kareh and Timothy W. Secomb, A Theoretical Model for Intraperitoneal Delivery of Cisplatin and the Effect of Hyperthermia on Drug Penetration Distance, Neoplasia. Vol. 6, No. 2, March/April 2004, pp. 117 – 127 https://doi.org/10.1593/neo.03205
  • Stefaan Mulier, Jean-Pierre Claes, Vincent Dierieck, Jean-Olivier Amiel , Jean-Philippe Pahaut , Luc Marcelis , Fabienne Bastin , Denis Vanderbeeken , Claude Finet , Sophie Cran et al. Survival Benefit of Adding Hyperthermic Intraperitoneal Chemotherapy (HIPEC) at the Different Time-points of Treatment of Ovarian Cancer: Review of Evidence, Current Pharmaceutical Design, 2012, 18, 3793-3803 https://doi.org/10.2174/138161212802002616
  • E. de Bree, M. Christodoulakis & D. Tsiftsis. Malignant peritoneal mesothelioma treated by continuous hyperthermic peritoneal perfusion chemotherapy, Annals of Oncology 11: 753-756, 2000.© 2000 Netherlands https://doi.org/10.1023/A:1008328120555
  • Irina V.Larina, B.Mark Evers, Taras V.Ashit Kov, Christian Barte Is, Kirill V.Larin and Rinat O. Esenliev.Enhancement of drug delivery in tumors by using interactions of nanoparticles with ultrasound radiation, Technology in cancer research and treatments. ISSN 1533-0346, Volume 4, Number 2, April (2005) https://doi.org/10.1177/153303460500400211
  • James.E.Nicholson. Selective enhancement 0f hyperthermia in RF and microwave irradiation of diseased or excess U'S' patent documents tissue, Patent Number: 6, 131, 577, Date of Patent: Oct. 17, 2000
  • John Kanzius, Erie, PA (US), enhanced systems and methods for Rf-induced hyperthermia ii, pub. No.: us 2007/0250139 a1, Pub. Date: Oct. 25, 2007
  • John Kanzius, enhanced systems and methods for rf-induced hyperthermia, United States patent application Publication, Pub. No.: US 2006/0190063, Pub. Date: Aug. 24, 2006
  • Dustin E. Kruse, Douglas N. Stephens et al., A Radio-frequency Coupling Network for Heating of Citrate coated Gold Nanoparticles for Cancer Therapy: Design and Analysis, IEEE Trans Biomed Eng. 2011 July ; 58(7): 2002–2012. Doi:10.1109/TBME.2011.2124460 https://doi.org/10.1109/TBME.2011.2124460
  • Melvin A. Astrahan, Los Alamitos, Paul F. Turner. Urethral Inserted applicator for prostate hyperthermia. Patent Number: 5,220,927, Date of Patent: Jun. 22, 1993
  • Kasevich et al. microwave systems for medical hyperthermia, thermotherapy and diagnosis, Patent Number: 6,097,985, Date of Patent: Aug. 1, 2000
  • Chen X, Diederich CJ, Wootton JH, Pouliot J, Hsu IC. Optimization-based thermal treatment planning for catheter-based ultrasound hyperthermia. Int J Hyperthermia. 2010 Feb; 26(1):39-55. Doi: 10.3109/02656730903341332. https://doi.org/10.3109/02656730903341332
  • Riadh W. Y. Habash, Rajeev Bansal, Daniel Krewski, andhafid T. Alhafid. Thermal Therapy, Part 2: Hyperthermia Techniques, Critical reviews in Biomedical Engineering, 34(6):491–542 (2006) https://doi.org/10.1615/CritRevBiomedEng.v34.i6.30
  • Piotr gas, study on interstitial microwave hyperthermia with multi-slot coaxial antenna, Rev. Roum. Sci. Techn. – Électrotechn. Et Énerg., 59, 2, p. 215–224, Bucarest, 2014
  • David Vrba and Jan Vrba. Novel Applicators for Local Microwave Hyperthermia Based on Zeroth-Order Mode Resonator Metamaterial. International Journal of Antennas and Propagation Volume 2014 (2014).Article ID 631398,7pageshttp://dx.doi.org/10.1155/2014/631398
  • Piotr gas. multi–frequency analysis for interstitial microwave hyperthermia using multi–slot coaxial antenna, journal of electrical engineering, vol. 66, no. 1, 2015, 26–33 https://doi.org/10.1515/jee-2015-0004
  • Hao-Yu Tseng, Chen-Yi Lee, Ying-Hsia Shih, Xi-Zhang Lin and Gwo-Bin Lee. Localized Heating of Tumor Cells Utilizing Super paramagnetic Nanoparticles, Proceedings of the 7th IEEE International Conference on Nanotechnology August 2 - 5, 2007, Hong Kong https://doi.org/10.1109/NANO.2007.4601345
  • Arkadiusz, Miaskowski and Bartosz Sawicki. Magnetic Fluid Hyperthermia Modelling Based on Phantom Measurements and Realistic Breast model, IEEE transactions on biomedical engineering, vol. 60, no. 7, July 2013 https://doi.org/10.1109/TBME.2013.2242071
  • Jiangtao Li, Zheng Liang, Xu Zhong, Zhijie Zhao, and Jianhao Li. Study on the Thermal Characteristics of Fe3O4 Nanoparticles and Gelatin Compound for Magnetic Fluid Hyperthermia In radiofrequency magnetic field, IEEE transactions on magnetics, vol. 50, no. 11, November 2014 https://doi.org/10.1109/TMAG.2014.2323411
  • M. Pavel, A. Stancu. Ferromagnetic Nanoparticles Dose Based on Tumor Size in Magnetic Fluid Hyperthermia Cancer Therapy, IEEE transactions on magnetics, Vol 45, NO. 11, November 2009 https://doi.org/10.1109/TMAG.2009.2031076
  • Issels R.D. Hyperthermia adds to chemotherapy. Eur. J. Cancer. 2008;44:2546–2554. doi: 10.1016/j.ejca.2008.07.038. https://doi.org/10.1016/j.ejca.2008.07.038
  • Issels R. Hyperthermia combined with chemotherapy—Biological rationale, clinical application, and treatment results. Oncol. Res. Treat. 1999;22:374–381. doi: 10.1159/000026986. https://doi.org/10.1159/000026986
  • Oei A.L., Vriend L.E., Crezee J., Franken N.A., Krawczyk P.M. Effects of hyperthermia on DNA repair pathways: One treatment to inhibit them all. Radiat. Oncol. 2015;10:165. doi: 10.1186/s13014-015-0462-0. https://doi.org/10.1186/s13014-015-0462-0
  • Vujaskovic Z., Kim D.W., Jones E., Lan L., McCall L., Dewhirst M.W., Craciunescu O., Stauffer P., Liotcheva V., Betof A., et al. A phase I/II study of neoadjuvant liposomal doxorubicin, paclitaxel, and hyperthermia in locally advanced breast cancer. Int. J. Hyperth. 2010;26:514–521. doi: 10.3109/02656731003639364. https://doi.org/10.3109/02656731003639364
  • Oldenborg S., Rasch C.R.N., van Os R., Kusumanto Y.H., Oei B.S., Venselaar J.L., Heymans M.W., Zum Vörde Sive Vörding P.J., Crezee H., van Tienhoven G. Reirradiation + hyperthermia for recurrent breast cancer en cuirasse. Strahlenther. Onkol. 2018;194:206–214. doi: 10.1007/s00066-017-1241-7 https://doi.org/10.1007/s00066-017-1241-7
  • Ferlay J., Ervik M., Lam F., Colombet M., Mery L., Piñeros M., Znaor A., Soerjomataram I., Bray F. Book Global Cancer Observatory: Cancer Today. International Agency for Research on Cancer; Lyon, France: 2020. Global cancer observatory: Cancer Today.
  • National Institute of Health. National Cancer Institute (NCI) NCI Issues Clinical Announcement on Cervical Cancer: Chemotherapy Plus Radiation Improves Survival. Chemotherapy Plus Radiation Improves Survival, 1999. [(accessed on 15 December 2017)]. Published 1999.
  • Datta N.R., Stutz E., Liu M., Rogers S., Klingbiel D., Siebenhuner A., Singh S., Bodis S. Concurrent chemoradiotherapy vs. radiotherapy alone in locally advanced cervix cancer: A systematic review and meta-analysis. Gynecol. Oncol. 2017;145:374–385. doi: 10.1016/j.ygyno.2017.01.033. https://doi.org/10.1016/j.ygyno.2017.01.033
  • Ohguri T, Harima Y, Imada H, Sakurai H, Ohno T, Hiraki Y, Tuji K, Tanaka M, Terashima H. Relationships between thermal dose parameters and the efficacy of definitive chemoradiotherapy plus regional hyperthermia in the treatment of locally advanced cervical cancer: data from a multicentre randomised clinical trial. International Journal of Hyperthermia. 2018 May 19;34(4):461-8. https://doi.org/10.1080/02656736.2017.1352105
  • Minnaar CA, Kotzen JA, Ayeni OA, Vangu MD, Baeyens A. Potentiation of the abscopal effect by modulated electro-hyperthermia in locally advanced cervical cancer patients. Frontiers in Oncology. 2020 Mar 24;10:376 https://doi.org/10.3389/fonc.2020.00376
  • Ferlay J., Ervik M., Lam F., Colombet M., Mery L., Piñeros M., Znaor A., Soerjomataram I., Bray F. Book Global Cancer Observatory: Cancer Today. International Agency for Research on Cancer; Lyon, France: 2020. Global cancer observatory: Cancer Today.
  • Lacas B., Carmel A., Landais C., Wong S.J., Licitra L., Tobias J.S., Burtness B., Ghi M.G., Cohen E.E.W., Grau C., et al. Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): An update on 107 randomized trials and 19,805 patients, on behalf of MACH-NC Group. Radiother. Oncol. 2021;156:281–293. doi: 10.1016/j.radonc.2021.01.013. https://doi.org/10.1016/j.radonc.2021.01.013
  • Verduijn GM, de Wee EM, Rijnen Z, Togni P, Hardillo JA, Ten Hove I, Franckena M, Van Rhoon GC, Paulides MM. Deep hyperthermia with the HYPERcollar system combined with irradiation for advanced head and neck carcinoma–a feasibility study. International Journal of Hyperthermia. 2018 Oct 3;34(7):994-1001. https://doi.org/10.1080/02656736.2018.1454610
  • Kroesen M, van Holthe N, Sumser K, Chitu D, Vernhout R, Verduijn G, Franckena M, Hardillo J, van Rhoon G, Paulides M. Feasibility, SAR distribution, and clinical outcome upon reirradiation and deep hyperthermia using the hypercollar3D in head and neck cancer patients. Cancers. 2021 Dec 6;13(23):6149. https://doi.org/10.3390/cancers13236149
  • Datta NR, Jain BM, Mathi Z, Datta S, Johari S, Singh AR, Kalbande P, Kale P, Shivkumar V, Bodis S. Hyperthermia: A Potential Game-Changer in the Management of Cancers in Low-Middle-Income Group Countries. Cancers (Basel). 2022 Jan 9;14(2):315. doi: 10.3390/cancers14020315. PMID: 35053479; PMCID: PMC8774274. https://doi.org/10.3390/cancers14020315
  • Larach MG, Localio AR, Allen GC, Denborough MA, Ellis FR, Gronert GA, Kaplan RF, Muldoon SM, Nelson TE, Ording H, Rosenberg H, Waud BE, Wedel DJ. A clinical grading scale to predict malignant hyperthermia susceptibility. Anesthesiology. 1994;80:771–9 https://doi.org/10.1097/00000542-199404000-00008
  • Litman RS, Rosenberg H. Malignant hyperthermia: update on susceptibility testing. JAMA: the journal of the American Medical Association. 2005;293:2918–24 https://doi.org/10.1001/jama.293.23.2918
  • Sambuughin N, Capacchione J, Blokhin A, Bayarsaikhan M, Bina S, Muldoon S. The ryanodine receptor type 1 gene variants in African American men with exertional rhabdomyolysis and malignant hyperthermia susceptibility. Clin Genet. 2009;76:564–8 https://doi.org/10.1111/j.1399-0004.2009.01251.x
  • Robinson R, Carpenter D, Shaw MA, Halsall J, Hopkins P. Mutations in RYR1 in malignant hyperthermia and central core disease. Human mutation. 2006;27:977–89. https://doi.org/10.1002/humu.20356
  • Carpenter D, Robinson RL, Quinnell RJ, Ringrose C, Hogg M, Casson F, Booms P, Iles DE, Halsall PJ, Steele DS, Shaw MA, Hopkins PM. Genetic variation in RYR1 and malignant hyperthermia phenotypes. Br J Anaesth. 2009;103:538–48. https://doi.org/10.1093/bja/aep204
  • Robinson RL, Carpenter D, Halsall PJ, Iles DE, Booms P, Steele D, Hopkins PM, Shaw MA. Epigenetic allele silencing and variable penetrance of malignant hyperthermia susceptibility. Br J Anaesth. 2009;103:220–5. https://doi.org/10.1093/bja/aep108
  • Tammaro A, Di Martino A, Bracco A, Cozzolino S, Savoia G, Andria B, Cannavo A, Spagnuolo M, Piluso G, Aurino S, Nigro V. Novel missense mutations and unexpected multiple changes of RYR1 gene in 75 malignant hyperthermia families. Clin Genet. 2011;79:438–47. https://doi.org/10.1111/j.1399-0004.2010.01493.x
  • Newmark JL, Voelkel M, Brandom BW, Wu J. Delayed onset of malignant hyperthermia without creatine kinase elevation in a geriatric, ryanodine receptor type 1 gene compound heterozygous patient. Anesthesiology. 2007;107:350–3. https://doi.org/10.1097/01.anes.0000271866.37280.85
  • Monnier N, Krivosic-Horber R, Payen JF, Kozak-Ribbens G, Nivoche Y, Adnet P, Reyford H, Lunardi J. Presence of two different genetic traits in malignant hyperthermia families: implication for genetic analysis, diagnosis, and incidence of malignant hyperthermia susceptibility. Anesthesiology. 2002;97:1067 –74. https://doi.org/10.1097/00000542-200211000-00007
  • Ibarra MC, Wu S, Murayama K, Minami N, Ichihara Y, Kikuchi H, Noguchi S, Hayashi YK, Ochiai R, Nishino I. Malignant hyperthermia in Japan: mutation screening of the entire ryanodine receptor type 1 gene coding region by direct sequencing. Anesthesiology. 2006;104:1146–54. https://doi.org/10.1097/00000542-200606000-00008
  • El-Ghety, H. S., Emam, I., El-Fishawy, N., & M. Ali, A. (2019). Engineering Cloud Based Platform to Enhance Radiation Oncology Services. In International Journal of Innovative Technology and Exploring Engineering (Vol. 8, Issue 11, pp. 2654–2658). Blue Eyes Intelligence Engineering and Sciences Engineering and Sciences Publication - BEIESP. https://doi.org/10.35940/ijitee.k1962.0981119
  • Anjaneyulu, B., & Sankar, Dr. A. B. (2020). Intensive Modulated Three-Dimensional Computed Tomography Radio Therapy. In International Journal of Recent Technology and Engineering (IJRTE) (Vol. 8, Issue 5, pp. 2437–2440). Blue Eyes Intelligence Engineering and Sciences Engineering and Sciences Publication - BEIESP. https://doi.org/10.35940/ijrte.e5075.018520