Published March 6, 2025 | Version v3
Model Open

StarDist2D Model for Nuclei Segmentation (Synthetic sir-DNA Images)

  • 1. Universidad Carlos III de Madrid Escuela Politécnica Superior

Description

This StarDist2D model segments nuclei from synthetic sir-DNA images, which were originally generated from Lifeact-RFP images using the Pix2Pix model. It forms the second step in a pipeline for image-to-image translation and segmentation.

This model is part of a use case from the paper:
Fuster-Barceló et al., 2024Bridging the gap: Integrating cutting-edge techniques into biological imaging with deepImageJ (Biological Imaging, 4, e14. doi:10.1017/S2633903X24000114).

It was fine-tuned using the ZeroCostDL4Mic notebook with a dataset from Zenodo and follows the BioImage Model Zoo format (bioimage.io) for compatibility with DeepImageJ.

- Fine-Tuning Notebook:StarDist Notebook
- Training Dataset: Zenodo Dataset

📌 For DeepImageJ users: Download the SyntheticsirDNA-StarDist2D.zip file for direct use, as Zenodo’s automatic zipping may cause issues.

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Additional details

Dates

Available
2023-12-21
Updated
2025-03-06

References

  • Schmidt, U., Weigert, M., Broaddus, C., & Myers, G. (2018). Cell detection with star-convex polygons. In Medical Image Computing and Computer Assisted Intervention–MICCAI 2018: 21st International Conference, Granada, Spain, September 16-20, 2018, Proceedings, Part II 11 (pp. 265-273). Springer International Publishing.
  • von Chamier, L., Laine, R. F., Jukkala, J., Spahn, C., Krentzel, D., Nehme, E., ... & Henriques, R. (2021). Democratising deep learning for microscopy with ZeroCostDL4Mic. Nature communications, 12(1), 2276.
  • Fuster-Barceló, C., García-López-de-Haro, C., Gómez-de-Mariscal, E., Ouyang, W., Olivo-Marin, J.-C., Sage, D., & Muñoz-Barrutia, A. (2024). Bridging the gap: Integrating cutting-edge techniques into biological imaging with deepImageJ. Biological Imaging, 4, e14. doi:10.1017/S2633903X24000114