Streptococcus Pneumoniae ST556 Vs Mycoplasma Pneumoniae M129 genome by Blastn analysis

Introduction: The overlap between Streptococcus pneumoniae and Mycoplasma pneumoniae genome was studied by Blastn analysis. Mycoplasma is an intracellular pathogen causing pneumonia with staccato cough, predominantly handled by T cell immunity. 

Methods: Through the NCBI website, the overlap of genome sequences of Streptococcus pneumoniae Taiwan (PT 306), and mycoplasma pneumoniae were studied using Blastn. The accession number for the Streptococcus pneumoniae ST556 was CP003357, and the Mycoplasma pneumoniae strain M129 was U00089, respectively. DNA alignments and nucleotide overlapping alignment sequences were studied.

Results: There were significant overlaps between the genome sequences of these two organisms by blastn. The overlapping sequences and dot analysis are shown in the files attached in this accompanying document. The overlapping nucleotides involved with high significance (expect values = 0.0).

Conclusion: There are overlaps in genome sequences between Streptococcus pneumoniae and mycoplasma genomes. Further studies are required to study the significance of the COVID-19 context and the recent outbreak of mycoplasma in the community across various countries. The overlap can throw some ideas of the use of the potential of streptococcus pneumoniae vaccines for prevention. If not a prevention Streptococcus pneumonia vaccinations can facilitate a deceleration in the spread of mycoplasma infections.