Published December 4, 2023 | Version v1
Dataset Open

Single-Cell RNA-Sequencing Reveals Placental Response under Environmental Stress

  • 1. Department of Biostatistics, Harvard School of Public Health, Boston, MA, USA
  • 2. Department of Environmental Medicine, School of Medicine and Dentistry, University of Rochester, Rochester, NY, USA
  • 3. Division of Allergy, Immunology and Rheumatology, Department of Medicine, University of Rochester, Rochester, NY, USA
  • 4. Department of Obstetrics and Gynecology, School of Medicine and Dentistry, University of Rochester, Rochester, NY, USA
  • 5. Department of Pediatrics, School of Medicine and Dentistry, University of Rochester, Rochester, NY
  • 6. Department of Statistics, Harvard University, Cambridge, MA, USA

Description

This repository provides scRNA-seq data corresponding to the manuscript "Single-Cell RNA-Sequencing Reveals Placental Response under Environmental Stress" by Van Buren, Azzara, Rangel-Moreno, de la Luz Garcia-Hernandez, Murphy, Cohen, Lin, and Park. The repository includes both count by gene matrices output from CellRanger version 6.0.1 (file names *_filtered_feature_matrix.h5 for each of the eight samples Control_1_M, Control_1_F, Control_2_M, Control_2_F, As_1_M, As_1_F, As_2_M, As_2_F), and a finalized Seurat object including cell type assignments as used for analyses in the manuscript (file name final_Seurat_obj.RData). Accompanying code used in analysis can be found at https://github.com/edvanburen/placenta_code.

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