Disulfide bridge-dependent dimerization triggers FGF2 membrane translocation into the extracellular space

GROMACS-2022 configuration and topologies (.itp, .tpr, .top, .mdp) and ROSETTA protein-protein docking files for reproducing unbiased and biased (umbrella sampling) atomistic molecular dynamics simulations.

AlphaFold2 Predictions

Full details of simulations are available in the related manuscript, where they are also carefully analyzed.

Reviewed Preprint available at: https://doi.org/10.7554/eLife.88579.2