Functional requirement analysis report of Use Case 1

The aim of WP7 is to demonstrate the utility of the envisioned HealthyCloud infrastructure by analysing real-world use cases for which specific research questions are addressed. The use case 1, led by Sciensano, focusses on cancer condition. It aims to assess how genomic information, gathered at the population level, can contribute to developing high-risk profiling for the major risk factors for cancer and other factors such as socio-economic status and health literacy. The deliverable 7.1 describes the necessary data for the use case including the existing Belgian data and the potential data from other countries (i.e., Finland, Spain and Germany) that may be included in future revisions. The problems encountered to access these data are described. A broad introduction to the statistical analysis for studying the effect of exposures to risk factors on the cancer outcome is provided. The functional requirements are expressed in terms of the analysis elements, addressed in Section 3, that will be latter included as inputs in Task 7.3 in conjunction with the functional requirements of D7.2.