Which species of NHP should be used to model PD?
- 1. Institute of Neurodegenerative Diseases, Bordeaux, France
Contributors
- 1. Lund University, Sweden
- 2. Molecular Imaging Research Center, CEA, Paris, France
- 3. Emory National Primate Research Center, Atlanta USA
- 4. University of Wisconsin, Madison
-
5.
University of Pittsburgh
- 6. Kyoto University Graduate School of Medicine
- 7. Centre for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan
- 8. California National Primate Research Center and Department of Neurology, School of Medicine, UC Davis
- 9. University of Wisconsin–Madison
- 10. NDRC, Arizona State University
Description
This document encapsulates key recommendations resulting from the PD-AGE workshop, focusing on the critical decision of choosing non-human primate (NHP) species for modelling Parkinson's disease (PD) and understanding the impact of ageing on PD pathology. Through comprehensive discussions with experts, the workshop leaders discussed the irreplaceable role of NHP models and identified an ideal NHP species to model PD. The document provides a rationale for these choices and serves as a valuable guide for researchers navigating the selection of NHP species in PD and ageing studies, fostering informed decisions and advancing translational research in this crucial field.
The expert panel in this workshop was: Benjamin Dehay, Erwan Bezard, Jia-Yi Li, Romina Aron-Badin, Yoland Smith, Marina E. Emborg, Simon Borgognon, Ryosuke Takahashi, Jun Takahashi, John H Morrison, Rozalyn Anderson, Ashley Boehringer, Calista Holt, Julia Gambardella
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Additional details
Funding
- Michael J. Fox Foundation