EFFECTS OF PENTOXIFYLLINE IN CHILDREN WITH MYOCARDITIS

Myocarditis is inflammation of the myocardium with necrosis of cardiomyocytes. Myocarditis can occur for various reasons (eg, infectious diseases, cardiotoxins, drugs, systemic diseases such as sarcoidosis), but is often idiopathic. Symptoms can vary and include fatigue, shortness of breath, swelling, palpitations, and sudden death. Diagnosis is based on symptoms and clinical findings on an abnormal electrocardiogram, cardiac biomarkers, and cardiac imaging in the absence of cardiovascular risk factors. Endomyocardial biopsy confirms the clinical diagnosis of myocarditis. Treatment depends on the cause, but common measures include medications to treat heart failure and arrhythmias, and rarely surgery (eg, intra-aortic balloon pump, left ventricular assist device, transplant). takes Immunosuppression is used in some types of myocarditis (for example, hypersensitivity myocarditis, giant cell myocarditis, sarcoid myocarditis).