Published October 31, 2023
| Version v2
Dataset
Open
Examination of the effect of nocadazole treatment on lipidomics
Creators
-
1.
The University of Texas MD Anderson Cancer Center
Description
We conducted an analysis to investigate the impact of Nocodazole treatment on Caki-1, a human renal cell carcinoma cell line. Our preliminary lipidomics analysis revealed that Nocodazole induces the accumulation of triacylglycerides (TAGs) in Caki-1 cells. To gain further insights, we employed inhibitors of diacylglycerol acyltransferases (DGATs), including DGAT1 and DGAT2, which play a pivotal role in TAG synthesis by adding a fatty acyl group to the sn-3 position of diacylglycerol, ultimately forming TAGs.
Files
Files
(8.9 GB)
| Name | Size | Download all |
|---|---|---|
|
md5:6601dc8b62774bb9854aad5938328011
|
371.9 MB | Download |
|
md5:ed807ecd461ce1fdd25feb9b19a23d46
|
349.6 MB | Download |
|
md5:1189320d253c6b2743d429b5a76d5e68
|
371.8 MB | Download |
|
md5:65dc6d4c0a650fa4c49763c7e13965ff
|
351.0 MB | Download |
|
md5:1d4f7784b219ee18a2d0b9ebe945a54e
|
372.7 MB | Download |
|
md5:50083351a93827039f7339ffbb6e52c6
|
350.3 MB | Download |
|
md5:c74529db864ced5133cb3f48efa77024
|
385.6 MB | Download |
|
md5:37020d23f6aa771fe777ba8b29f3dc60
|
357.0 MB | Download |
|
md5:0dc80be89ff7480b00bc8bee7251a1fe
|
375.7 MB | Download |
|
md5:3213e4a589aa1c0380f48ff500a94f48
|
354.0 MB | Download |
|
md5:5e3605063ac0c79410523691409b7af3
|
382.7 MB | Download |
|
md5:3497bf7bc25e2267cb4f6d5fc60712de
|
356.0 MB | Download |
|
md5:9c7cc7e5032fe539966c403faa8cf67c
|
379.1 MB | Download |
|
md5:62966274f88251b382699f309d870805
|
361.7 MB | Download |
|
md5:61848ea06be51fc93091b3655f5f34ba
|
380.0 MB | Download |
|
md5:75b97074f8e9f98b13f3c5b262ba6d9a
|
351.7 MB | Download |
|
md5:7af15519c5085626d72454dfe14daad6
|
388.1 MB | Download |
|
md5:0ec8cf7209241841df9de1e810827c76
|
348.7 MB | Download |
|
md5:78faba5c8dc911b4dc822e606c926ba8
|
407.1 MB | Download |
|
md5:d70d865df52d87ed5ed163bef2728581
|
391.0 MB | Download |
|
md5:0509d4ba02b27e404c2be512dd5ff454
|
392.1 MB | Download |
|
md5:82296b0957daba42413122b4b711774b
|
381.1 MB | Download |
|
md5:39904b8c31fd2149855ea901bc9a9081
|
385.9 MB | Download |
|
md5:85179495123e1c6cfbb266bcb249650c
|
376.1 MB | Download |
|
md5:17703107b998acf5e85b2f7ed91323d7
|
182.7 kB | Download |
|
md5:325aea9f26f52272393705fb491a0936
|
10.1 kB | Download |