Published June 21, 2024 | Version v1
Dataset Open

seurat objects of FACS-sorted (CD31+/CD45-) endothelial cells - overall merges

  • 1. ROR icon ETH Zurich

Description

Seurat objects of overall merges of FACS-sorted (CD31+/CD45-) endothelial cells
-> part of the manuscript: Single-cell atlas of the human brain vasculature across development, adulthood and disease
https://www.nature.com/articles/s41586-024-07493-y

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-i) Overall merge of all brain sorted endothelial cells_seurat object.rds: 
     -> this seurat object is the overall merge of FACS-sorted (CD31+/CD45-) endothelial cells isolated from fetal brain, adult/control brains (temporal lobes), brain tumors (lower-grade glioma, high-grade glioma (glioblastoma), brain metastasis, meningiomas) and brain vascular malformations (brain arteriovenous malformations). 

-ii) Overall merge of all sorted brain and peripehry endothelial cells_seurat object.rds: 
     -> this seurat object is the overall merge of FACS-sorted (CD31+/CD45-) endothelial cells isolated from fetal brain, fetal peripheral organs, adult/control brains (temporal lobes), brain tumors (lower-grade glioma, high-grade glioma (glioblastoma), brain metastasis, meningiomas) and brain vascular malformations (brain arteriovenous malformations). 

-iii) Overall merge of pathological sorted endothelial cells_seurat object.rds: 
     -> this seurat object is the overall merge of FACS-sorted (CD31+/CD45-) endothelial cells isolated from brain tumors (lower-grade glioma, high-grade glioma (glioblastoma), brain metastasis, meningiomas) and brain vascular malformations (brain arteriovenous malformations). 

-iv) Overall merge of tumor sorted endothelial cells_seurat object.rds: 
     -> this seurat object is the overall merge of FACS-sorted (CD31+/CD45-) endothelial cells isolated from brain tumors (lower-grade glioma, high-grade glioma (glioblastoma), brain metastasis, meningiomas). 

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Subtitle (English)
overall merges of FACS-sorted (CD31+/CD45-) endothelial cells

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Is published in
Journal article: 10.1038/s41586-024-07493-y (DOI)