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Published October 27, 2023 | Version 0.4.0
Software Open

pdimens/harpy: v0.4.0

Authors/Creators

  • 1. Cornell University

Description

New features

  • naibr variant calling now relies on whatshap to back-phase BAM files from a phased VCF for much, much better variant calling
  • harpy preflight to do a full suite of file format validations on bam/fastq files prior to running one of the main modules
  • lots more file-check validations and helpful error messages before harpy hands things over to snakemake
  • regular RMarkdown reports have been completely revised using R::Flexdashboard

bugfixes

  • More file checks means fewer downstream errors
  • typos corrected

breaking changes

TL;DR: This release pretty much breaks every aspect of the the previous APIs. Pretend you've never used Harpy before

  • no more --method flag, instead methods have been submodule-arized into
    • harpy align --method bwa ... is now harpy align bwa ...
    • harpy align --method ema... is now harpy align ema ....
    • harpy variants snp --method... is now harpy snp method .... (method = freebayes or mpileup)
    • harpy variants sv --method...is nowharpy sv method ....(method =leviathanornaibr`)
  • harpy extra has been made into submodules too, now making:
    • harpy popgroup to create the popgroup file
    • harpy stitchparams to create the STITCH parameter file
    • harpy hpc to create a SLURM hpc profile

Files

pdimens/harpy-0.4.0.zip

Files (73.9 MB)

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Additional details

Related works

Is supplement to
Software: https://github.com/pdimens/harpy/tree/0.4.0 (URL)