CFdb: interactomes
Description
This upload contains predicted interactomes for 23 species derived from meta-analysis of co-fractionation mass spectrometry (CF-MS) data. The following individual organisms are represented:
- Arabidopsis thaliana
- Brassica oleracea
- Caenorhabditis elegans
- Chaetomium thermophilum
- Chlamydomonas reinhardtii
- Dictyostelium discoideum
- Drosophila melanogaster
- Glycine max
- Homo sapiens
- Mus musculus
- Nematostella vectensis
- Oryza sativa
- Plasmodium berghei
- Plasmodium falciparum
- Plasmodium knowlesi
- Saccharomyces cerevisiae
- Strongylocentrotus purpuratus
- Triticum aestivum
- Trypanosoma brucei
- Xenopus laevis
- Escherichia coli
- Anabaena sp. PCC 7120
- Synechocystis sp. PCC 6803
Network inference was performed by training a random forest classifier on known complexes (from CORUM or EcoCyc, for eukaryotes and prokaryotes respectively) to predict interacting protein pairs in cross-validation. Files include the complete classifier scores for every possible protein pair, sorted in descending order. The resulting networks can then be thresholded at an arbitrary precision.
Files
Files
(3.1 GB)
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md5:055cabd78c4e594b3ccb8dfeee2b0fb3
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133.0 MB | Download |
md5:193db92663b85c729d60a8cd38babd83
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8.3 MB | Download |