Plants as an Alternative System for Expression of Vaccine Antigens

As a demand for vaccine production continues to grow, new innovative approaches and cell substrates for vaccine antigen expression are being developed. Recently, an increasing interest in using plants for recombinant protein production, including vaccine antigens and therapeutic antibodies, has been observed. Here, we overview plant-based expression systems and discuss their advantages, including high and most rapid production capacity, relatively low capital investment, and freedom from contamination with animal pathogens.