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CORBEL Core set of outcome measures for clinical trials for each disease condition

Battaglia, Serena; Da Silva-Buttkus, Patricia; Demotes, Jacques; Fuchs, Helmut; Gailus-Durner, Valérie; Garattini, Silvio; Harman, Nicola; Prinsen, Cecilia; Raess, Michael; Terwee, Caroline; Williamson, Paula

Animal models play a crucial role in understanding the mechanisms of diseases and symptoms, and to test the efficacy and safety of treatments before conducting clinical trials. Selecting human diseases and developing core sets of clinical outcome measures as well as complementary sets of mouse phenotyping measures will contribute to narrow the gap between animal models and human trials.

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