A STUDY OF BIOCHEMICAL RESPONSE IN CATTLE IMMUNIZED WITH BM95 RECOMBINANT VACCINE
Creators
- 1. Department of Veterinary Parasitology A.N.D.U.A.T., Kumarganj, Ayodhya-224229, (U.P.)- India
Description
Ticks are very common ectoparasites of bovine and other domestic ruminants across the world. The bovine tick Boophilus annulatus and B. microplus have been estimated to cause an annual weight loss of 0.7 kg/tick. They have also been found to spread serious protozoal diseases like Babesiosis, Anaplasmosis among cattle and buffaloes in India. In the present study, twelve healthy cattle divided into two groups (A and B) of six animals in both the groups. Engorged adult Boophilus microplus female ticks were reared for hatching and larval emergence. Bm95 recombinant tick antigen was obtained from Indian Immunological Ltd., Hyderabad, India. Group A was inoculated with 1 ml of antigen on zero day and second dose in the same amount on 15th day after primary dose and group B kept as unvaccinated control. All animals were challenged with larval ticks on 30th day, 70th day and 120th day post vaccination. Blood samples were collected on zero day and weekly interval till one month and then fortnightly up to 5 months. Globulin, Albumin and Total serum protein (TSP) values were significant (P<0.01) increased whereas the values of Alanine aminotransferase (ALT) and Aspartate aminotransferase (AST) were significant (P<0.01) decreased in group A (Bm95) animals as compared to control animals.
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References
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