CHARACTERISTICS OF THE IMMUNE SYSTEM IN PATIENTS CHILDREN WITH HIV AND CHRONIC TONSILLITIS

The article studied the immune parameters in children with a combined course of HIV pathology and chronic tonsillitis. In both groups of patients with chronic tonsillitis on the background of HIV infection there was a significant suppression of cellular parameters. We can also highlight the disorder of B(CD19)-the cellular link of the immune system. If in the 1st group there was a tendency towards a decrease in IgA and IgG levels and an increase in IgM, then in the 2nd group only a decrease in the IgA content was found. In contrast, the levels of IgM (p<0.05) and IgG in patients of the 2nd group were higher than those of the control group. If in the 2nd group there were more intense disorders of immunological parameters, in the 1st group of patients clinical symptoms were more pronounced.

Patients of the 1st group with prenatal infection by characteristic symptoms of chronic tonsillitis were common bacterial infections, generalized lymphadenopathy, viral infections, etc. against the background of deep prematurity.  In patients of the 2nd group with a vertical pathway of HIV infection, chronic tonsillitis was accompanied by a more pronounced depression of the immune system and a relatively lower occurrence of clinical symptoms.