Published September 20, 2023 | Version v1
Journal article Open

PHARMACOTHERAPEUTIC PROPERTIES OF DRUGS USED IN THE TREATMENT OF GASTRIC ULCER

Description

The two-stage scheme of gastric ulcer treatment is the most effective:

Stage I lasts 7 days. During this period, the patient is prescribed a combination of two antibiotics, usually metronidazole and clarithromycin, as well as a proton pump inhibitor such as lansoprazole. Medicines can be replaced with analogues at the discretion of the attending physician, and the dose is determined individually. The goal of the first stage of treatment is to completely eliminate Helicobacter pylori, and in 95% of cases this task can be overcome;

Stage II lasts 14 days and is required only if Helicobacter pylori is found in the stomach after the first stage. A tandem of metronidazole + tetracycline antibiotics is used against bacteria, and the therapy is supplemented with one of the bismuth drugs, as well as PPIs (omeprazole, rabeprazole) and histamine receptor blockers (ranitidine, famotidine).

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