Published August 21, 2023 | Version v1
Journal article Open

Guardians of Health: How the Virome Influences Immunity and Disease

  • 1. 1*Junior Research Fellow at Eastern Regional Station, ICAR-Indian Veterinary Research Institute (ICAR-IVRI), Kolkata, West Bengal 700037, India 2Research Scholar, West Bengal University of Animal and Fishery Sciences, Department of Veterinary Biochemistry, 37 and 68, khudiram Bose Sarani, Belgachia, Kolkata 700037, India

Description

In the intricate interplay between the human body and the microbial world, the virome emerges as a captivating frontier of exploration, wielding profound influences over immunity and disease. While the study of bacteria and their effects on human health has received much attention, the viral occupants of our bodies have come to be seen as equally important regulators of both wellness and disease. Akin to a silent yet potent guardian, the virome comprises of a diverse array of viruses inhabiting various niches within the human body. These viruses not only engage in dynamic interactions with the host's immune system but also form complex networks with other microbes. Recent progressions in metagenomic sequencing have illuminated the previously uncharted terrain of the virome, allowing scientists to unravel its hidden dimensions and decipher its effect on human health.

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