Published July 31, 2022
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Fig. 4. Compounds 1, 21 in Six C21 steroidal glycosides from Cynanchum wallichii Wight roots and their multidrug resistance reversal activities
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Fig. 4. Compounds 1, 21, and 25 can reverse drug resistance by decreasing P-gp, NF-κB, and c-jun gene and protein expression. (A–C) MDR1, NFκB, and JUN gene expression in MCF-ADR and HepG2-ADM cells following co-treatment with 1, 21, and 25 and Doxorubicin. (D–E) MDR1, NFκB, and Jun protein expression in MCFADR and HepG2-ADM cells treated with 1, 21, and 25 in combination with DOX.
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Published as part of Zhang, Ludi, Yuefang, Lin, min, Huang, Wenbo, Chen, Duan, Lixin, Liu, Zhongqiu, Lu, Linlin & Zhang, Rong-Rong, 2022, Six C21 steroidal glycosides from Cynanchum wallichii Wight roots and their multidrug resistance reversal activities, pp. 1-10 in Phytochemistry (113172) 199 on page 8, DOI: 10.1016/j.phytochem.2022.113172, http://zenodo.org/record/8234715
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- Journal article: 10.1016/j.phytochem.2022.113172 (DOI)
- Journal article: urn:lsid:plazi.org:pub:FFD9FF904622520844190129E43DFFD6 (LSID)
- Journal article: https://zenodo.org/record/8234715 (URL)