Published January 31, 2023
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Fig. 6. Compound 14 in Diterpenoids with anti-inflammatory activity from Euphorbia wallichii
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- 1. ** & * & Wuya College of Innovation, School of Traditional Chinese Materia Medica, Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education,
Description
Fig. 6. Compound 14 reduced LPS-induced pro-inflammatory cytokines release. (A) The NO inhibition curve of compound 14, with an IC50 of 3.84 ± 0.25 μM. (B) Cell viability rate of RAW264.7 cells treated with compound 14 (0, 3.125, 6.25, 12.5, 25, 50, 100 μM) for 24 h. (C–D) Effects of compound 14 on production of inflammatory cytokines (IL-6 and TNF-α) in LPS-induced RAW264.7 cells. ###, p <0.001 vs. control group. *, p <0.1, **, p <0.01 and ***, p <0.001 vs. LPStreated group.
Notes
Published as part of Wang, Yali, Sun, Dejuan, Jiang, Qinghua, Xiong, Liangliang, Zhang, Na, Pan, Yingni, Li, Hua & Chen, Lixia, 2023, Diterpenoids with anti-inflammatory activity from Euphorbia wallichii, pp. 1-11 in Phytochemistry (113486) 205 on page 6, DOI: 10.1016/j.phytochem.2022.113486, http://zenodo.org/record/8230709
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- Journal article: 10.1016/j.phytochem.2022.113486 (DOI)
- Journal article: urn:lsid:plazi.org:pub:FFE9457170538252F349A916FF8BFFC3 (LSID)
- Journal article: https://zenodo.org/record/8230709 (URL)