Published August 3, 2023
| Version v1
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CNCA aligns small annotated genomes
- 1. Université Paris Cité, F-75006 Paris, France; CNRS, Institut Jacques Monod, F-75013 Paris, France; SMILE group, Center for Interdisciplinary Research in Biology (CIRB), Collège de France, F-75006 Paris, France.
- 2. Université Paris Cité, F-75006 Paris, France; CNRS, Matière et Systèmes Complexes, F-75013 Paris, France.
- 3. Université Paris Cité, F-75006 Paris, France; CNRS, Institut Jacques Monod, F-75013 Paris, France
- 4. Université Paris Cité, F-75006 Paris, France; SMILE group, Center for Interdisciplinary Research in Biology (CIRB), Collège de France, F-75006 Paris, France
Description
We present CNCA, an online tool to align annotated genomes from GenBank files. It generates a nucleotide alignment that is then updated based on the protein sequence alignment. The output final nucleotide alignment matches the protein alignment and guarantees no frameshift. CNCA was designed to aligned closely related small genome sequences up to 50 kb (typically viruses) for which the gene order is conserved.
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Additional details
Funding
- Université de Paris – Université de Paris ANR-18-IDEX-0001
- Agence Nationale de la Recherche
- WHO AM I – Determinants de l'Identité : de la molécule à l'individu ANR-11-LABX-0071
- Agence Nationale de la Recherche