GENOME-WIDE ASSOCIATION STUDIES (GWAS) HAVE REVOLUTIONIZED OUR VIEW OF HUMAN HEALTH AND DISEASE GENETICS AND OFFERED NOVEL GENE THERAPY TARGETS

Knowing how genetic, behavioural, and sociocultural factors influence each person's risk for
C. It is imperative that a larger, more diverse set of genetic studies be done in order to be able
to close the analysis of CMD distance In terms of disease prevention, there is a lot of interest
in CMD genomic research. This potential can only be achieved if Ancestry DNA-style data
like PRS is successfully gathered from the population. Inadequate participation is a big issue
in current CMD genetic research. Differential minorities in the United States and Canada have
set forth some important steps to improve their access to genetic research. To make sure that
this will not happen again, these activities include discovering the issues and using communitybased
participatory interventions and benefits-sharing mechanisms. People underrepresented
in the world of genetics will require more services to support them.
CMD and other genomics markers have been successfully identified and created novel avenues
for human and population health change. In addition, it has complicated matters with regard to
how this data would affect the broader healthcare system. What are the main questions:
disproportionate difficulty in the CMD genotype-phenotype database; confounded research on
disease heritability; ethnicity may not be well described, making estimating disease heritability
difficultDespite these roadblocks, genome-informed inclusive data will bear unprecedented
promise for bringing down CMD and improving wellbeing. A large-scale data unification has
already occurred, as mentioned in this blog post to CMD Data sharing, however, is a project
that must be done on a small scale in order to gain initial traction. This is also applicable to
GWAS research on self-identified ethnicity. Although race and ethnicity are socially and
culturally constructed, the use of self-identifying categories in genetic studies still endures.