Clinicohaematological and Biochemical Profile of Anemia in Pediatric Age Group
Creators
- 1. Assistant Professor, Patna Medical College and Hospital Patna, Bihar
- 2. Senior Resident, Patna Medical College and Hospital Patna, Bihar
Description
Background: Anemia is a prevalent hematological disorder in the pediatric population, affecting child health and development. Understanding the clinicohaematological and biochemical profile of anemia in children is crucial for accurate diagnosis and effective management.
Methods: This cross-sectional study investigated the clinicohaematological and biochemical profile of anemia in pediatric patients. A sample of 200 children (aged 1-12 years) with confirmed anemia was included. Relevant clinical data, hematological parameters, and biochemical markers were collected. Hemoglobin levels, serum iron, red blood cell indices, and ferritin levels were analyzed. Statistical analysis, including correlation and subgroup comparisons, was performed to identify associations between clinical, hematological, and biochemical variables.
Results: The average age of the study's participants was 6.8 years at the time it was conducted. There were 200 individuals in total, including 120 males and 80 women. Hematological testing revealed that iron deficiency anemia accounted for 65% of all cases of anemia. Hemolytic anemia accounted for 20% of all cases of anemia, followed by all other varieties of anemia combined, which accounted for 15%. Using diagnostic criteria that are unique to each type of anemia, we discovered statistically significant differences in hematological parameters. Those with iron deficiency anemia have statistically significantly lower serum iron and ferritin concentrations than those with other forms of anemia (p 0.001). There was evidence of an interaction between hematological and biochemical indicators in cases of juvenile anemia.
Conclusion: This study provides insights into the clinicohaematological and biochemical anemia profile in a sample of 200 pediatric patients. Iron deficiency anemia was the most common type, followed by hemolytic anemia and other classes. Hematological and biochemical parameters differed significantly among anemia types, with lower serum iron and ferritin levels observed in iron deficiency anemia cases. The findings emphasize the importance of comprehensive evaluation, including hematological and biochemical parameters, for accurate diagnosis and management of anemia in children. Further research is needed to explore additional contributing factors and develop targeted interventions for prevention and treatment.
Abstract (English)
Background: Anemia is a prevalent hematological disorder in the pediatric population, affecting child health and development. Understanding the clinicohaematological and biochemical profile of anemia in children is crucial for accurate diagnosis and effective management.
Methods: This cross-sectional study investigated the clinicohaematological and biochemical profile of anemia in pediatric patients. A sample of 200 children (aged 1-12 years) with confirmed anemia was included. Relevant clinical data, hematological parameters, and biochemical markers were collected. Hemoglobin levels, serum iron, red blood cell indices, and ferritin levels were analyzed. Statistical analysis, including correlation and subgroup comparisons, was performed to identify associations between clinical, hematological, and biochemical variables.
Results: The average age of the study's participants was 6.8 years at the time it was conducted. There were 200 individuals in total, including 120 males and 80 women. Hematological testing revealed that iron deficiency anemia accounted for 65% of all cases of anemia. Hemolytic anemia accounted for 20% of all cases of anemia, followed by all other varieties of anemia combined, which accounted for 15%. Using diagnostic criteria that are unique to each type of anemia, we discovered statistically significant differences in hematological parameters. Those with iron deficiency anemia have statistically significantly lower serum iron and ferritin concentrations than those with other forms of anemia (p 0.001). There was evidence of an interaction between hematological and biochemical indicators in cases of juvenile anemia.
Conclusion: This study provides insights into the clinicohaematological and biochemical anemia profile in a sample of 200 pediatric patients. Iron deficiency anemia was the most common type, followed by hemolytic anemia and other classes. Hematological and biochemical parameters differed significantly among anemia types, with lower serum iron and ferritin levels observed in iron deficiency anemia cases. The findings emphasize the importance of comprehensive evaluation, including hematological and biochemical parameters, for accurate diagnosis and management of anemia in children. Further research is needed to explore additional contributing factors and develop targeted interventions for prevention and treatment.
Files
IJPCR,Vol15,Issue7,Article9.pdf
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(319.3 kB)
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Additional details
Dates
- Accepted
-
2023-06-05
Software
- Repository URL
- https://impactfactor.org/PDF/IJPCR/15/IJPCR,Vol15,Issue7,Article9.pdf
- Development Status
- Active
References
- 1. P. Upadhyay and S. R. Kanetkar, Clinicohematological profile of anemia in pediatric (newborn to eighteen years) age group, International Journal of Health Sciences and Research, 2022; 12(2):260–265. 2. S. R. Barbind and D. N. Hambire, Assessment of prevalence of anemia and study of anemic patients in population of Nanded District, International Journal of Advances in Medicine, 2020; 7(12):1836. 3. A. N. Shah, J. S. Kothari, D. P. Desai, T. Savaliya, and R. B. Prajapati, Clinical and biochemical outcome in pediatric patients with iron deficiency anemia, International Journal of Contemporary Pediatrics, 2020; 7(11):2146. 4. H. Aldeen Hameed, O. Abbood Khalil, E. Wissam, and J. I Alezzi, Epidemiological study of anemia in Diyala Province / Iraq, Diyala Journal of Medicine, 2021; 20(1):11– 16. 5. S. Gugloth, M. Otiv, and A. Pandit, Study of prevalence of iron deficiency anemia in hospitalized children in Tertiary Care Centre, Perspectives in Medical Research, 2022; 10(1):95–98. 6. M. A. Tayab, M. A. Hoq, and M. Begum, Cut off value of red cell distribution width (RDW) in screening and diagnosis of iron deficiency anemia and B thalassemia trait, Dhaka Shishu (Children) Hospital Journal, 2022; 37(1): 51– 58. 7. I. Jamal, S. Shuchismita, and V. Choudhary, Twin malignancy of acute myeloid leukemia and multiple myeloma in a chemotherapynaïve patient: A rare occurrence, Journal of Laboratory Physicians, 2022. 8. R. Kumar et al., Nutritional anemia in children in post supplementation era: A Cross Sectional Study, Asian Journal of Medical Sciences, 2021; 12(6): 44–49. 9. G. Mishra and R. Dwivedi, Clinicoaetiological analysis of anemia along with hematological parameters in children and adolescents: A retrospective study from a Tertiary Care Hospital, Chhattisgarh, India, Journal Of Clinical And Diagnostic Research, 2022. 10. S. Saranappa and J. Wu, A clinical study of anemia in children aged 6 months–5 years in a tertiary care center, Bengaluru, Karnataka, India, Indian Journal of Child Health, 2021; 8(10): 367–370. 11. P. Kalaiselvam, S. Chelliah, and M. Pachamuthu, Prevalence of nutritional anemia in children of high socioeconomic status in a tertiary care center, Indian Journal of Child Health, 2021; 8(10): 359–361. 12. R. Kumar et al., Nutritional anemia in children in post supplementation era: A Cross Sectional Study, Asian Journal of Medical Sciences, 2021; 12(6): 44–49. 13. P. Kalaiselvam, S. Chelliah, and M. Pachamuthu, Prevalence of nutritional anemia in children of high socioeconomic status in a tertiary care center, Indian Journal of Child Health, 2021; 8(10): 359–361. 14. P. J. Solomon, M. Chellaraj, and A. P. Margaret, Anemia in Indian children and management, Scholars Journal of Applied Medical Sciences, 2021; 9(7): 1185–119. 15. S. Saranappa and J. Wu, A clinical study of anemia in children aged 6 months–5 years in a tertiary care center, Bengaluru, Karnataka, India, Indian Journal of Child Health, 2021; 8(10): 367–370.