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Published March 10, 2023 | Version v1
Journal article Open

Detection of E.coli 23S rRNA by electrocatalytic "off-on" DNA beacon assay with femtomolar sensitivity

Creators

  • 1. Interdisciplinary Nanoscience Center (iNANO) and Aarhus University Center for Water Technology (WATEC), Faculty of Science, Aarhus University
  • 2. Department of Environmental Science, Aarhus University

Description

This work developed a fast and fM sensitive electrocatalytic “off-on” biosensing platform utilizing MB-labelled hairpin DNA beacons immobilized on Au screen printed electrodes. This platform was appied for analysis of rRNA extracted from E. coli. 

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Additional details

Funding

BREAK BIOFILMS – Breaking Bad Biofilms. Innovative Analysis and Design Rules for Next-Generation Antifouling Interfaces 813439
European Commission