HYPOLIPIDEMIC ACTIVITY OF POLYHERBAL FORMULATION IN TRITON WR-1339 INDUCED HYPERLIPIDEMIC RATS

Hyperlipidemia is the greatest risk factor of coronary heart disease. Currently available synthetic hypolipidemic drugs have been associated with number of side effects compare with herbal formulation, Anti Diabetic formulation was selected and the present study on anti-hyperlipidemic

activity against triton induced hyperlipidemia in rats. Anti-diabetic formulation Administered at a dose of 200μg/kg (p.o) to the triton induced hyperlipidemic rats. Anti-diabetic formulation has shown a significant decrease in the levels of serum cholesterol, triglyceride, LDL, VLDL and significant increase in the level of serum HDL. Whereas fraction of anti-diabetic formulation decreased serum level of total cholesterol, LDL and increased the serum HDL cholesterol level.

Keywords: Polyherbal, Hyperlipidemia, LDL, VLDL, HDL.