First Case of Splenic Abscess Parvimonasmicra and Bacteremia Porphyromonagingivalis Coinfection
- 1. Touro College of Osteopathic Medicine, Middletown, NY, United States
- 2. Putnam Hospital Center, Putnam, NY. United States
Description
Abstract
Porphyromonagingivalis and Parvimonasmicra are anaerobic microorganisms that are usually found in the normal oral microbiome. Bacteremiais rarely caused by P. gingivalis and there have been no reports of splenic abscess caused by P. micra. Treatments for P. micra include vancomycin, ceftriaxone, and metronidazole, while treatments for P. gingivalis include tetracyclines, macrolides, beta-lactam penicillins, and clindamycin. We report a case of a 76-year-old caucasian male with bacteremia caused by P. gingivalis and splenic abscess caused by P. micra. This patient presented with nonspecific symptoms: fever, chills, body aches, and shortness of breath. He was treated with IV piperacillin-tazobactam that was later switched to ampicillin sodium/sulbactam sodium during his hospital course and underwent a splenectomy. He ultimately expired due to acute respiratory failure and cardiac arrest, secondary to post-surgical complications. To our knowledge, this is the first case of P. micra and P. gingivalis coinfection.
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References
- How KY, Song KP, Chan KG. Porphyromonasgingivalis:An Overview of Periodontopathic Pathogen below the Gum Line. Front Microbiol. 2016 Feb;7:53.
- Petersen PE, Ogawa H. The global burden of periodontal disease: towards integration with chronic disease prevention and control. Periodontol 2000. 2012 Oct;60(1):15-39.
- Lee SC, Fung CP, Lin CC, Tsai CJ, Chen KS.Porphyromonas gingivalis bacteremia and subhepaticabscess after renal transplantation: a case report. J MicrobiolImmunol Infect. 1999 Sep;32(3):213-216.
- Smith DA, Nehring SM. Bacteremia. [Updated 2021 Jul25]. StatPearls [Internet]. Treasure Island (FL): Stat Pearls Publishing; 2022 Jan-. Accessed March 15, 2022.
- Chassagne P, Perol MB, Doucet J, Tivalle C, Menard JF,et al. Is presentation of bacteremia in the elderly the sameas in younger patients? Am J Med. 1996 Jan;100(1):65-70.
- Gomez CA, Gerber DA, Zambrano E, Banaei N,Dereskinski S, et al. First case of infectious endocarditis caused by Parvimonasmicra. Anaerobe. 2015 Dec;36:53-55.
- Cobo F, Rodríguez-Granger J, Sampedro A, AliagaMartínez L, Navarro-Marí JM. Pleural effusion due toParvimonasmicra. A case report and a literature review of30 cases. Rev Esp Quimioter. 2017 Aug;30(4):285-292.
- Kim EU, Baek YH, Jung DS, SookWoo K. ConcomitantLiver and Brain Abscesses Caused by Parvimonasmicra.Korean J Gastroenterol. 2019 Apr;73(4):230-234.
- Watanabe T, Hara Y, Yoshimi Y, Fujita Y, Yokoe M, etal. Clinical characteristics of bloodstream infection byParvimonasmicra: retrospective case series and literaturereview. BMC Infect Dis. 2020 Aug;578.
- Chaucer B, Smith N, Beatty D, Yadav M. MultipleHepatic Abscess from Parvimonasmicra: An EmergingGastrointestinal Microbe. ACG Case Rep J. 2018Sep;5:e70.
- Garrido-Jareño M, Frasquet-Artes J, Tasias-PitarchM, López-Hontangas JL. Primer caso de absceso renalporParvimonasmicra. EnfermInfeccMicrobiolClin. 2019Feb;37:140-141.
- Hoch J. Splenic Abscess and Infarction – Rare Eventsfor which Surgery is Mandatory. European Surgery. 2003Dec;35:321-324.
- Sawai T, Koga S, Ide S, Yoshioka S, Matsuo N. An iliopsoasabscess caused by Parvimonasmicra: a case report. J MedCase Reports. 2019 Mar;13(1):47.
- Lee WS, Choi ST, Kim KK. Splenic abscess: a singleinstitution study and review of the literature. Yonsei Med J.2011 Mar;52(2):288-292.
- Johnson JD, Raff MJ, Barnwell PA, Chun CH. Splenicabscess complicating infectious endocarditis. Arch Intern Med. 1983 May;143(5):906-912.
- Lotfollahzadeh S, Mathew G, Zemaitis MR. SplenicAbscess. [Updated 2021 Dec 3]. In: StatPearls [Internet].Treasure Island (FL): StatPearls Publishing; 2022 Jan-.Accessed March 16, 2022.
- Ardila CM, López MA, Guzmán IC. High resistance against clindamycin, metronidazole and amoxicillin in Porphyromonas gingivalis and Aggregatibacteractinomycetemcomitans isolates of periodontal disease. Med Oral Patol Oral Cir Bucal. 2010Nov;15(6):e947-e951.
- Raghavendran K, Nemzek J, Napolitano LM, Knight PR. Aspiration-induced lung injury. Crit Care Med. 2011Apr;39(4):818-826.