Azcorra2023 - Raw fiber photometry recordings
Description
Raw data from fiber photometry recordings of different subtypes (Vglut2+, Calb1+, Anxa1+ and Aldh1a1+ as well as DAT+) SNc dopamine neurons labelled with GCaMP6f, as used in Azcorra et al. Nat Neuro 2023. Metadata for these recordings (recording location, mouse sex...) can be found in the pre-processed dataset (see below).
The code used to pre-processed this data to get DF/F is available on GitHub (https://github.com/DombeckLab/Azcorra2023/releases/tag/Azcorra2023) and Zenodo (DOI: 10.5281/zenodo.7872052, https://zenodo.org/record/7872052). We have also made the pre-processed data available on Zenodo (DOI: 10.5281/zenodo.7871982, https://zenodo.org/record/7871982). The code necessary to analyze this data and generate the figures shown in the manuscript is is found in that same GitHub repository as the pre-processing code above.
Notes
Files
2020-02-26 Vglut2.zip
Files
(33.9 GB)
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Additional details
Related works
- Is supplemented by
- Dataset: 10.5281/zenodo.7871982 (DOI)
- Software: 10.5281/zenodo.7900531 (DOI)
Funding
- Redefining PD pathophysiology mechanisms in the context of heterogeneous substantia nigra neuron subtypes ASAP-020600
- Aligning Science Across Parkinson's