Published December 15, 2022
| Version v3
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Supplementary material - Non-invasive Multimodal Imaging Reveals Early Therapy-Induced Senescence in Human Cancer Cells
Authors/Creators
- 1. Department of Physics, Politecnico di Milano, P.zza Leonardo da Vinci 32, 20133 Milan, Italy
- 2. Department of Mechanical Engineering, Johns Hopkins University, Baltimore, Maryland, USA
- 3. IRCCS Istituto Nazionale dei Tumori Foundation, Milan, Italy
- 4. IRCCS Istituto Nazionale dei Tumori Foundation, Milan, Italy, Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA , The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
- 5. Department of Physics, Politecnico di Milano, P.zza Leonardo da Vinci 32, 20133 Milan, Italy, CNR-Institute for Photonics and Nanotechnologies (IFN-CNR), P.zza Leonardo Da Vinci 32, 20133 Milan, Italy
Description
The repository features .xls and .txt worksheets including all the data used through this work and reported in the manuscript figures and graphs. More precisely, we included the following:
- Figure 2. Raw pixel-wise signals detected in NLO images of TIS cells control cells that were used to perform the colocalization graphs and analyses reported. We describe the average colocalization of SRS and F-CARS signals, and TPEF and E-CARS signals, in both phenotypes.
- Figure 4. Raw data from image analyses of TPEF and SRS channels of multimodal NLO images, divided in 5 different time points over the therapy follow-up period. The data describe the early rearrangement of mitochondria (TPEF) and lipid vesicles (SRS) in TIS cells, with respect to control counterparts.
- Figure 6. Raw data from image analyses of QPI images, divided in 4 different time points over the therapy follow-up period. The data describe the early morphological modifications of TIS cells, with respect to control counterparts.
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Figure2_NLOcolocalization.zip
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