Published June 27, 2024 | Version v2
Dataset Open

Data for "The glucocorticoid receptor potentiates aldosterone-induced transcription by the mineralocorticoid receptor"

Creators

  • 1. Laboratory of Receptor Biology and Gene Expression, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
  • 2. Department of Physics, University of Maryland, College Park, MD, USA
  • 3. Department of Biochemistry and Molecular Biology 2, CIBERehd, School of Pharmacy, Instituto de Investigación Biosanitaria ibs.GRANADA, Instituto de Nutrición y Tecnología de los Alimentos José Mataix, University of Granada, 18071 Granada, Spain
  • 4. Department of Pharmacology, CIBERehd, School of Pharmacy, Instituto de Investigación Biosanitaria ibs.GRANADA, University of Granada, 18071 Granada, Spain
  • 5. Institute for Physical Science and Technology, University of Maryland, College Park, MD, USA
  • 6. Departamento de Ciencias Médicas Básicas and Instituto de Tecnologías Biomédicas, Universidad de La Laguna, Campus de Ciencias de la Salud sn, 38200 San Cristóbal de La Laguna, Spain

Description

This deposit contains all the single-molecule trajectories reported in "The glucocorticoid receptor potentiates aldosterone-induced transcription by the mineralocorticoid receptor".

To access the tracks, open the mat file in MATLAB. This contains a MATLAB table with the following fields:

summary_table.cell_protein{i} identifies the ith dataset i.e. cell line + protein + treatment.

summary_table.X{i}{j} is an Nx2 array of x and y coordinates (in microns) for track j in condition i. N is the number of localizations in that track.

Time interval between localizations is 200 ms.

Details on data acquisition and tracking parameters can be found in the associated manuscript.

Files

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