EPIDEMIOLOGICAL, CLINICAL – EVOLUTIONARY AND DIAGNOSTIC ASPECTS OF HODGKIN'S LYMPHOMA

Hodgkin's lymphoma (LH) or lymphogranulomatosis is a neoplasia of the lymphatic tissue, which can affect people of different ages [1]. LH can appear in any decade of life, but most frequently at the age of 16-35[2]. REEDSternberg cells represent a pathognomonic sign for classic LH [3]. The clinical picture does not involve any specific signs [2]. Most patients present lymphadenopathy, and the lymph nodes most frequently are the primary focus [4]. The diagnosis is established by performing biopsy of the affected lymph node or the suspected organ. Epidemiological, clinical – evolutionary and diagnostic aspects of Hodgkin’s lymphoma were studied in 60 patients, diagnosed with Hodgkin’s lymphoma (HL), from the database of PMSI Oncologic Institute, Chisinau, Republic of Moldova. All the evaluated cases were morphologically confirmed. It was determined that HL developed more frequently up to the age of 35 years (41,7%). The recurrence of the appearance of HL by gender showed a prevalence of men - 53%, 32 patients out of 60.