Published April 20, 2023 | Version 1
Dataset Open

Ergolide Mediates Anti-Cancer Effects on Metastatic Uveal Melanoma Cells and Modulates their Cellular and Extracellular Vesicle proteomes

Authors/Creators

  • 1. UCD Conway Institute, University College Dublin, Dublin, Ireland; UCD School of Biomolecular and Biomedical Science, University College Dublin, Dublin, Ireland; Systems Biology Ireland, University College Dublin, Dublin, Ireland; UCD School of Medicine, University College Dublin, Dublin, Ireland
  • 2. UCD Conway Institute, University College Dublin, Dublin, Ireland; UCD School of Biomolecular and Biomedical Science, University College Dublin, Dublin, Ireland; Xenopat S.L., Business Bioincubator, Bellvitge Health Science Campus, 08907 L'Hospitalet de Llobregat, Barcelona, Spain
  • 3. Systems Biology Ireland, University College Dublin, Dublin, Ireland
  • 4. Department of Surgery, Trinity Translational Medicine Institute, Trinity St. James's Cancer Institute, St. James's Hospital, Trinity College Dublin, Dublin, Ireland
  • 5. UCD Conway Institute, University College Dublin, Dublin, Ireland; UCD School of Biomolecular and Biomedical Science, University College Dublin, Dublin, Ireland
  • 6. Medical Oncology Department, Catalan Institute of Cancer (ICO), IDIBELL-OncoBell, Barcelona, Spain
  • 7. Pharmahungary Group, Szeged, Hungary; Department of Pharmacology and Pharmacotherapy, Semmelweis University, Budapest, Hungary
  • 8. Institute of Experimental Medicine, Budapest, Hungary
  • 9. UCD Conway Institute, University College Dublin, Dublin, Ireland
  • 10. Department of Genetics and Immunobiology, Semmelweis University, Budapest, Hungary
  • 11. Pharmahungary Group, Szeged, Hungary
  • 12. Systems Biology Ireland, University College Dublin, Dublin, Ireland; UCD School of Medicine, University College Dublin, Dublin, Ireland
  • 13. BioReperia AB, Linköping, Sweden

Description

Underlying dataset and extended dataset of the results described in the article "Ergolide Mediates Anti-Cancer Effects on Metastatic Uveal Melanoma Cells and Modulates their Cellular and Extracellular Vesicle proteomes".

Notes

The project was supported by grants from the National Research, Development and Innovation Office (NKFIH) of Hungary (FK134751 to K139105 to ZG and VEKOP-2.3.3-15-2017-00016). Project no. TKP2021-EGA-23 has been implemented with the support provided by the Ministry of Innovation and Technology of Hungary from the National Research, Development and Innovation Fund, financed under the TKP2021-EGA funding scheme. The study was also funded by Project no. RRF-2.3.1-21-734907 and the Comprehensive Molecular Analysis Platform (CMAP) initiative under The SFI Research Infrastructure Programme in 2019, reference 18/RI/5702.

Files

Extended Dataset Figures.pdf

Files (12.9 MB)

Name Size Download all
md5:ed333b45dcde3008714a4fee52f89709
8.6 MB Download
md5:93ae2ac873234a3c4255905eafe96baa
834.4 kB Download
md5:61da672d511a5d5de9cf389f8245d557
1.1 MB Preview Download
md5:25b0683e477b61581ef0217cd6ae4e81
57.4 kB Download
md5:1f278893b9896633786308f238e4620d
49.0 kB Download
md5:7f1ef9223d1224101d7efe8597f51961
1.4 MB Download
md5:f5394f162a9d2ff156c0f0e305ca4ee4
576.2 kB Download
md5:647900da5ee67a558897179c48b8b328
330.7 kB Preview Download

Additional details

Funding

European Commission
3D NEONET - Drug Discovery and Delivery NEtwork for ONcology and Eye Therapeutics 734907
European Commission
CRYSTAL3 - Commercial & Research Opportunity for Cysteinyl Leukotriene Signalling in Ocular & CNS Dysfunction, Cancer and Cardiovascular Disease 101007931
European Commission
TOPMed10 - Fellowship Programme supporting Career Development and Interdisciplinary Training in Omics driven Personalised Medicine 666010