Parkinson's diagnosis hybrid system based on deep learning classification with imbalanced dataset

Brain degeneration involves several neurological troubles such as Parkinson’s disease (PD). Since this neurodegenerative disorder has no known cure, early detection has a paramount role in improving the patient’s life. Research has shown that voice disorder is one of the first symptoms detected. The application of deep learning techniques to data extracted from voice allows the production of a diagnostic support system for the Parkinson’s disease detection. In this work, we adopted the synthetic minority oversampling technique (SMOTE) technique to solve the imbalanced class problems. We performed feature selection, relying on the Chi-square feature technique to choose the most significant attributes. We opted for three deep learning classifiers, which are long-short term memory (LSTM), bidirectional LSTM (Bi-LSTM), and deep-LSTM (D-LSTM). After tuning the parameters by selecting different options, the experiment results show that the D-LSTM technique outperformed the LSTM and Bi-LSTM ones. It yielded the best score for both the imbalanced original dataset and for the balanced dataset with accuracy scores of 94.87% and 97.44%, respectively.