Published November 15, 2022
| Version v1
Software
Open
Biophysical 3D modeling of actin-mediated structural plasticity
Description
Simulation of dendritic spine enlargement upon LTP stimulation using PDEs for actin, arp2/3, and cofilin dynamics in a moving boundary framework.
Run Simulation_main.m
For the remeshing function (remeshing.m) see https://github.com/christopherhelf/isotropicremeshing/blob/master/README.md and the instructions therein.
Notes
This work was supported by the NIH Grant Number 1RF1DA055668-01 and by an Air Force Office of Scientific Research Grant FA9550-18-1-0051 to P.R.
Files
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(348.7 MB)
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Additional details
Related works
- Is supplement to
- Preprint: 10.1101/2022.11.06.515372 (DOI)