Ameliorative effect of aqueous leaf extract of Moringa oleifera on diabetes induced appetite and testicular weight loss in Wistar rats

The aim of this study was to determine the ameliorative effect of aqueous leaf extract of Moringa oleifera on diabetes induced appetite and testicular weight loss in wistar rats. Freshly harvested leaves of Moringa oleifera was processed into powder and subsequently extract. Thirty (30) adult male wistar rats were divided into six groups of five rats each. Group 1 was the normal control which was only fed with rat chow and water ad libitum. Group II was induced with diabetes without treatment, Group III-V were induced with diabetes prior to treatment with 100, 200, and 400 mg/kg bw respectively, while Group VI was induced with diabetes and subsequently treated with standard drug. Animal feed intake and weight of the harvested testicle from the rats were determined using standard procedures. The testicular weight as well as feed intake of the untreated diabetic rats were significantly (P<0.05) low compared to that reported for the control (Group I). However, this observation was significantly (P<0.05) reversed in treated diabetic rats in a dose dependent manner. This study reveals that Moringa oleifera can promote testicular health through its anti-diabetic potential.