Published June 22, 2023 | Version v1
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WAPL functions as a rheostat of Protocadherin isoform diversity that controls neural wiring

  • 1. University of California San Francisco
  • 2. Ecole Normale Superieure de Lyon
  • 3. University of California Berkeley
  • 4. Pura Vida Investments, New Yor

Description

Diverse neural wiring patterns emerge from differential regulation of cohesin-mediated DNA loop-extrusion by WAPL, which functions as a rheostat of cohesin processivity and Pcdh isoform diversity.

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Is cited by
Journal article: 10.1126/science.adf8440 (DOI)