A REVIEW ON FORMULATION OF CONVENTIONAL DRUG DELIVERY SYSTEM AND NOVEL DRUG DELIVERY SYSTEM

The formulation development is important part of pharmaceutical development and essential
for therapeutic and commercial success of product by providing quality, safety and efficiency.
Conventional drug delivery involves the formulation of the drug into a suitable form, such as
a compressed tablet for oral administration or a solution for intravenous administration. Novel
drug delivery systems (NDDS) are carriers which maintain the drug concentration in
therapeutic range for longer period of time. The amount of drug in a tablet can be a limiting
step in formulation design. Oral liquids are formulated as solutions, suspensions and
emulsions depending on the nature of the active ingredient particularly solubility and
stability. In formulation of any dosage form the various excipients such as coloring agent,
flavoring agents, glidandants, binders etc. are added. Gastroretentive dosage forms greatly
improved the pharmacotherapy of the Parenteral preparation should be isotonic with blood
plasma or other body fluids. The isotonicity of the solution may be adjusted by adding sodium
chloride, dextrose and boric acid etc. GIT through local drug release In this article
formulation of conventional such as tablets, capsules, semisolids, etc. and in NDDS
formulation of Controlled drug delivery system, GRDDS etc. are given. Nose to brain drug
delivery system in which drug transport through nasal route to CNS(central nervous system).
The main aim of these review is providing a needfull information of excipients and various
apporoaches are used in conventional drug delivery system and novel drug delivery system.