Proposal Open Access
Frangi, AF; Denison, T; Lincoln, J
Computational Modelling and Simulation (CM&S), sometimes referred to as in silico methods, are omnipresent in almost every industry sector and rely on sound engineering and science principles (e.g., automotive, aerospace and microelectronics) but with a slow uptake in pharma and med-tech. The InSilicoUK Innovation Network advocates unlocking the UK Life Sciences strategy and delivering upon the Life Sciences Vision by ensuring the UK has a strong regulatory science foundation that protects and advances public health. This foundation needs to modernise and embrace the potential and opportunities open up by digital data, modelling, and simulation. Amongst others, the recently published Landscape Report & Industry Survey on the Use of Computational Modeling & Simulation in Medical Device Development by the Medical Device Innovation Consortium articulated how CM&S can lead to safer, faster, and more cost-effective innovations for patient benefit.
We are a coalition of actors with academic, industrial, standardisation, compliance testing, policy and regulation background convinced in-silico technologies can support areas currently held back by the incumbent regulatory framework. They can cement the UK’s position as a global hub for health & life sciences R&D. Finally, they can drive economic growth and the creation of skilled jobs, levelling up across the country and supporting inward investment. This report explores the impact on some aspects of the UK’s economy that will be impacted or enabled by in-silico approaches to innovation and regulatory evidence creation. Our findings provide evidence that in-sliico approaches can drive economic prosperity and demands for highly skilled jobs.
Our main findings:
Following its public kick-off of the InSilicoUK Innovation Network in Mar 2022, the network continues to advocate for in-silico technology in the UK and provides evidence for its adoption in the UK while globally coordinating with Avicenna Alliance and the Medical Devices Innovation Consortium. The first report published by InnovateUK-Beahurst Report on In-silico Medicine focused on UK entrepreneurial activity, innovation funds, venture capital, and start-ups in this domain. For more information, follow us at www.insilicouk.org and https://twitter.com/InSilicoUK
Source: Frangi AF, Denison T & Lincoln, J (2023). The Economic Impact of In-silico Technology on the UK and its Lifesciences Sector. Report. https://doi.org/10.5281/zenodo.7558649
Ecomomic Impact of In Silico_v5.pdf
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