Dataset Open Access

Multivariate adaptive shrinkage improves cross-population transcriptome prediction for transcriptome-wide association studies in underrepresented populations

Araujo, Daniel S; Nguyen, Chris; Hu, Xiaowei; Mikhaylova, Anna V; Gignoux, Chris; Ardlie, Kristin; Taylor, Kent D; Durda, Peter; Liu, Yongmei; Papanicolaou, George; Cho, Michael H; Rich, Stephen S; Rotter, Jerome I; NHLBI TOPMed Consortium; Im, Hae Kyung; Manichaikul, Ani; Wheeler, Heather E

This Zenodo file collection contains transcriptome prediction models built for PrediXcan, as well as concatenated raw results from SPrediXcan. Files belong to the scientific research paper: "Multivariate adaptive shrinkage improves cross-population transcriptome prediction for transcriptome-wide association studies in underrepresented populations". Please refer to the README file for a more detailed description.

Files (1.5 GB)
Name Size
Mono_AFA_EN_baseline.db
md5:e33621033d19d6a7c5548ea5b523cf9d 		23.1 MB Download
Mono_AFA_EN_baseline_covariances.txt.gz
md5:66a0392b34c46d8c8ec08677494d0bb5 		29.0 MB Download
Mono_AFA_mashr_baseline.db
md5:afe4d26610731b8ba41f2a59c62118f0 		1.5 MB Download
Mono_AFA_mashr_baseline_covariances.txt.gz
md5:8aff350176a7842d262d85567d3e5dfa 		155.0 kB Download
Mono_AFA_matrixeQTL_baseline.db
md5:09138b806b656391f97444b9f79b59e6 		1.7 MB Download
Mono_AFA_matrixeQTL_baseline_covariances.txt.gz
md5:075a1c0685adee4acae11bf48882a129 		654.9 kB Download
Mono_EUR_EN_baseline.db
md5:8dc45228ec4237937e0ca6d255a70426 		29.0 MB Download
Mono_EUR_EN_baseline_covariances.txt.gz
md5:daf1e34199eb4dfcb2056a4d21e15b67 		35.9 MB Download
Mono_EUR_mashr_baseline.db
md5:d2133202dc5364a6f1edb0c7843ba10a 		1.5 MB Download
Mono_EUR_mashr_baseline_covariances.txt.gz
md5:e9d4739a85a390535125b0dbfac5d160 		192.5 kB Download
Mono_EUR_matrixeQTL_baseline.db
md5:1216dd12d47dcc2197b15c7738adca08 		1.6 MB Download
Mono_EUR_matrixeQTL_baseline_covariances.txt.gz
md5:6e16872e5a9b96c8dce909010561b7b3 		689.5 kB Download
Mono_HIS_EN_baseline.db
md5:0995ed595f3c88a3268acd898223ff6f 		23.7 MB Download
Mono_HIS_EN_baseline_covariances.txt.gz
md5:5a4276df5ba4828b4cd087b14a809021 		30.3 MB Download
Mono_HIS_mashr_baseline.db
md5:22e22e4ab89e3c5327c56e8fea2ac77d 		1.5 MB Download
Mono_HIS_mashr_baseline_covariances.txt.gz
md5:6cef4fc3a2fe8a8ead0307627fd97ac6 		199.7 kB Download
Mono_HIS_matrixeQTL_baseline.db
md5:f908fe460b839bda298d6226f93aed93 		1.7 MB Download
Mono_HIS_matrixeQTL_baseline_covariances.txt.gz
md5:8318b04d060d658d1d60cda5576296c9 		845.4 kB Download
PBMC_AFA_EN_baseline.db
md5:e6742c179f8a7e312d44ddfe04e6b54b 		62.9 MB Download
PBMC_AFA_EN_baseline_covariances.txt.gz
md5:4b2d942bfc901fe5766ed9e7bfbc2111 		113.7 MB Download
PBMC_AFA_mashr_baseline.db
md5:477f87da1324199812f2a949ec421644 		4.4 MB Download
PBMC_AFA_mashr_baseline_covariances.txt.gz
md5:b9f46e8e4e7bcc9bd1d7b3d78c9a6c83 		788.6 kB Download
PBMC_AFA_matrixeQTL_baseline.db
md5:7ee608c8766f9ec9e87b3f87a9ce18fd 		4.9 MB Download
PBMC_AFA_matrixeQTL_baseline_covariances.txt.gz
md5:6ca589349a513230c135d7a9c5155358 		1.7 MB Download
PBMC_CHN_EN_baseline.db
md5:b400345bb086043b59c3c4a449891aae 		37.9 MB Download
PBMC_CHN_EN_baseline_covariances.txt.gz
md5:b69792b9199c1f231d780cc70f5f8aae 		44.5 MB Download
PBMC_CHN_mashr_baseline.db
md5:ba7fff4acc4c3abd0af49c4b4f3a3146 		4.4 MB Download
PBMC_CHN_mashr_baseline_covariances.txt.gz
md5:83e63206673425e9f542383b7add8299 		550.8 kB Download
PBMC_CHN_matrixeQTL_baseline.db
md5:999ae51de5e395bed766c089c140da30 		4.4 MB Download
PBMC_CHN_matrixeQTL_baseline_covariances.txt.gz
md5:4f2229304c7370ce03097a260c62d4de 		1.0 MB Download
PBMC_EUR_EN_baseline.db
md5:426ca9ec927e6d598fb797a3f7f1ca13 		59.2 MB Download
PBMC_EUR_EN_baseline_covariances.txt.gz
md5:b814bed20102cad1e20e2753844da3c6 		88.5 MB Download
PBMC_EUR_mashr_baseline.db
md5:8a0ef0d134120cc8b17a5a56bbc07fd7 		4.4 MB Download
PBMC_EUR_mashr_baseline_covariances.txt.gz
md5:6992bf474e9f2f152ccc585fb3bad5f1 		751.8 kB Download
PBMC_EUR_matrixeQTL_baseline.db
md5:c1d70d3cdcc8f52ef6f93edddb13935d 		4.5 MB Download
PBMC_EUR_matrixeQTL_baseline_covariances.txt.gz
md5:1c5d5387c9c8f21e1f74782ffc976fc3 		1.4 MB Download
PBMC_HIS_EN_baseline.db
md5:17794d468b4a95f406737adda27664e1 		59.3 MB Download
PBMC_HIS_EN_baseline_covariances.txt.gz
md5:78ef909fa8213767149f8462c4653c03 		78.9 MB Download
PBMC_HIS_mashr_baseline.db
md5:971bc7ee0fe55c1f753c3a8be7cc5e93 		4.4 MB Download
PBMC_HIS_mashr_baseline_covariances.txt.gz
md5:5035452b750c104e64b9f2dcd3c5b480 		737.7 kB Download
PBMC_HIS_matrixeQTL_baseline.db
md5:8c356db9184d85ff475bfe8489c213ba 		4.9 MB Download
PBMC_HIS_matrixeQTL_baseline_covariances.txt.gz
md5:32caa153d2426ad41dba11e3288109b8 		1.6 MB Download
README.txt
md5:de31a4f72a3ce456678c39e38e1523da 		1.7 kB Download
SPrediXcan_PAGE_PanUKBB_raw_results.csv.gz
md5:389406cadcb2f3fa32dddf4afd89244f 		516.8 MB Download
Tcell_AFA_EN_baseline.db
md5:0cd63a695b6acec7d04fe3589faf2fa8 		24.0 MB Download
Tcell_AFA_EN_baseline_covariances.txt.gz
md5:9cccc29ad5fec3550fa405aeac118f2a 		30.0 MB Download
Tcell_AFA_mashr_baseline.db
md5:2167f2247b693974c2bd30d0628880cb 		1.6 MB Download
Tcell_AFA_mashr_baseline_covariances.txt.gz
md5:3d46a71702933baf5f2e22d555ace41a 		161.8 kB Download
Tcell_AFA_matrixeQTL_baseline.db
md5:c322e528051ce63164821abdca90f95f 		1.8 MB Download
Tcell_AFA_matrixeQTL_baseline_covariances.txt.gz
md5:5ed436eae6adca299129ad9b4cd16f74 		736.1 kB Download
Tcell_EUR_EN_baseline.db
md5:88a8b158d6e01f98ffee02230bdf255e 		31.5 MB Download
Tcell_EUR_EN_baseline_covariances.txt.gz
md5:4565682170553151824fd26a7084fc58 		39.0 MB Download
Tcell_EUR_mashr_baseline.db
md5:30324c02aa71a2282dd187e6c9e9aad4 		1.6 MB Download
Tcell_EUR_mashr_baseline_covariances.txt.gz
md5:f98b22eb8c3cfd95d67ca700088613fb 		207.9 kB Download
Tcell_EUR_matrixeQTL_baseline.db
md5:4c7b2a02fa2d7aff605bcf4d93deebea 		1.7 MB Download
Tcell_EUR_matrixeQTL_baseline_covariances.txt.gz
md5:3298eabe58ac65437d49ed97ee9ab24b 		824.9 kB Download
Tcell_HIS_EN_baseline.db
md5:824cf318521f94ac744670d190f6a2e2 		24.7 MB Download
Tcell_HIS_EN_baseline_covariances.txt.gz
md5:de601b6fb2d401b83e55350a602ecb0f 		31.3 MB Download
Tcell_HIS_mashr_baseline.db
md5:1761253c3b75b8ad660eb29a0c11bad9 		1.6 MB Download
Tcell_HIS_mashr_baseline_covariances.txt.gz
md5:7b95e67cc2e247b22d08aaf6e34ec5fc 		203.1 kB Download
Tcell_HIS_matrixeQTL_baseline.db
md5:de7d047d757087eae21adfabede15b5b 		1.8 MB Download
Tcell_HIS_matrixeQTL_baseline_covariances.txt.gz
md5:d4662da3fbd52c20e105bb9c87181da9 		935.4 kB Download
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Publication date:
January 19, 2023
DOI:
10.5281/zenodo.7551845

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Keyword(s):
MetaXcan PrediXcan TOPMed TWAS
License (for files):
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